1-(2-Pyrimidyl)piperazine CAS 20980-22-7 Purity >98.5% (HPLC)

Short Description:

Chemical Name: 1-(2-Pyrimidyl)piperazine

Synonyms: 2-(1-Piperazinyl)pyrimidine 

CAS: 20980-22-7

Purity: >98.5% (HPLC) 

Appearance: Pale Yellow Liquid or Solid 

High Quality, Commercial Production

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E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 1-(2-Pyrimidyl)piperazine (CAS: 20980-22-7) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name 1-(2-Pyrimidyl)piperazine 
Synonyms 2-(1-Piperazinyl)pyrimidine; 2-Piperazin-1-Ylpyrimidine; 2-Piperazin-1-yl-Pyrimidine; 2-Piperazinopyrimidine; 4-(2-Pyrimidinyl)piperazine;  N-2-Pyrimidinylpiperazine; PmP; 1-PP 
Impurity  Buspirone EP Impurity A; Buspirone Related Compound A
CAS Number 20980-22-7 
CAT Number RF2491
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C8H12N4  
Molecular Weight 164.21   
Melting Point 31.0~35.0℃
Boiling Point 118.0~120.0℃/2 mmHg
Density 1.158 g/cm3 at 25℃(lit.)
Sensitive Hygroscopic. Air Sensitive, Moisture Sensitive 
Solubility in Water Solubility in Water, Very Faint Turbidity
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Pale Yellow Liquid or Solid (Low-Melting)
Identitication HPLC The retention time of major peak of the sample solution should correspond to that of reference standard.
Purity / Analysis Method >98.5% (HPLC) 
Refractive Index n20/D 1.585~1.588
Moisture (K.F) <0.50%
Related Substances (HPLC) 
Bispyrimidinyl-Piperazine <0.50%
Unknown Single Impurity <0.50%
Total Impurities <1.50%
Infrared Spectrum Conforms to Structure
Proton NMR Spectrum Conforms to Structure
Test Standard Enterprise Standard
Note Low Melting Point, May Change State in Different Environments (Solid, Liquid or Semi-Solid)
Usage Pharmaceutical Intermediates; Organic Intermediates

Package & Storage:

Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Excellent quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

1-(2-Pyrimidyl)piperazine (CAS: 20980-22-7) is a piperazine-based derivative, is used for organic Intermediate or pharmaceutical intermediate. It is a metabolite of Buspirone, is an impurity of Buspirone, Buspirone EP Impurity A . Buspirone binding to serotonin 5-HTIA receptors in the brain, which is reduces symptoms of anxiety,also produces improvements in the comorbid disorder. 1-(2-Pyrimidyl)piperazine belongs to the class of organic compounds known as n-arylpiperazines. These are organic compounds containing a piperazine ring where the nitrogen ring atom carries an aryl group. 1-(2-Pyrimidyl)piperazine may be used for the following studies: As derivatization reagent for the carboxyl groups on peptides; Carboxy group derivatization during the spectrophotometric analysis of phosphopeptides; Starting reagent for the synthesis of 3-{(4-(Pyrimidin-2-yl)piperazin-1-yl)methyl}-1H-pyrrolo[2,3-b]pyridine; Synthesis of 3-Phenyl-6-(4-(pyrimidin-2-yl)piperazin-1-yl)pyridazin-4-ol.

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