1-(3-Methyl-1-Phenyl-5-Pyrazolyl)piperazine CAS 401566-79-8 Purity >99.5% (HPLC) Teneligliptin HBr Intermediate Factory
Supply Teneligliptin Hydrobromide Related Intermediates With High Purity
Teneligliptin Hydrobromide CAS 906093-29-6
1-(3-Methyl-1-Phenyl-5-Pyrazolyl)piperazine CAS 401566-79-8
Teneligliptin Hydrobromide Intermediate CAS 401564-36-1
| Chemical Name | 1-(3-Methyl-1-Phenyl-5-Pyrazolyl)piperazine |
| Synonyms | 1-(3-Methyl-1-Phenyl-1H-Pyrazol-5-yl)piperazine; Teneligliptin Impurity A |
| CAS Number | 401566-79-8 |
| CAT Number | RF-PI1817 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C14H18N4 |
| Molecular Weight | 242.32 |
| Density | 1.19 |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | Off-White to Light Brown Solid |
| Identification | IR; HPLC RT |
| Loss on Drying | <0.50% |
| Purity / Analysis Method | >99.5% (by HPLC) |
| Assay | >99.5% (On Dried Basis) |
| Single Impurity | <0.50% |
| Test Standard | Enterprise Standard |
| Usage | Intermediates of Teneligliptin HBr (CAS: 906093-29-6) |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
1-(3-Methyl-1-Phenyl-5-Pyrazolyl)piperazine (CAS: 401566-79-8) is an intermediate used to prepare Teneligliptin HBr (CAS: 906093-29-6). Teneligliptin HBr is a DPP-4 inhibitor which was approved in Japan in 2012 for the treatment of type II diabetes. Teneligliptin HBr was discovered and developed by Mitsubishi Tanabe Pharma under the trade name Tenelia®. Similar to other marketed DPP-4 inhibitors, Teneligliptin was well tolerated in all studies and QD dosing produced a long-lasting inhibitory action against DPP-4 and an increase in active GLP-1 levels, with very low rates of renal excretion.
