1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine CAS 340041-91-0 Purity >98.0% (HPLC) Almotriptan Malate Intermediate Factory

Short Description:

Name: 1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine

CAS: 340041-91-0

Purity: >98.0% (HPLC) 

Intermediate of Almotriptan Malate (CAS: 181183-52-8)

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com


Product Detail

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Description:

Chemical Properties:

Chemical Name 1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine
Synonyms N-[(4-Nitrophenyl)-methylsulfonyl]pyryolidine; 1-((4-Nitrobenzyl)sulfonyl)pyrrolidine
CAS Number 340041-91-0
CAT Number RF-PI1959
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C11H14N2O4S
Molecular Weight 270.30
Brand Ruifu Chemical

Specifications:

Item Specifications
Purity / Analysis Method >98.0% (HPLC)
Loss on Drying <1.00%
Test Standard Enterprise Standard
Usage Intermediate of Almotriptan Malate (CAS: 181183-52-8)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

1

FAQ:

Application:

1-[(4-Nitrophenylmethyl)sulfonyl]pyrrolidine (CAS: 340041-91-0) is an intermediate in the Preparation of Almotriptan Malate (CAS: 181183-52-8). Almotriptan Malate is an agonist of the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D (IC50s=12 and 13 nM, respectively, in a radioligand binding assay). Almotriptan Malate (LAS 31416) is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults. Almotriptan, marketed in 2000, has the highest oralbioavailability among all triptans. It is metabolizedby both MAO-A and CYP3A4, thus has a more favorableside effects profile when compared with Sumatriptan. 

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