(R)-(-)-3-Carbamoymethyl-5-Methylhexanoic Acid CAS 181289-33-8 Purity >99.0% (HPLC) Pregabalin Intermediate Factory

Short Description:

(R)-(-)-3-Carbamoymethyl-5-Methylhexanoic Acid 

CAS: 181289-33-8

Purity: >99.0% (HPLC)  

Appearance: White or Off-White Crystalline Powder

Intermediate of Pregabalin (CAS: 148553-50-8) 

Contact: Dr. Alvin Huang  

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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181289-33-8 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (R)-(-)-3-Carbamoymethyl-5-Methylhexanoic Acid (CAS: 181289-33-8) with high quality, commercial production, intermediate of Pregabalin (CAS: 148553-50-8). Ruifu Chemical can provide worldwide delivery, small and bulk quantities available, strong after-sale service. Welcome to order. Please contact: alvin@ruifuchem.com

181289-33-8 - Chemical Properties:

Chemical Name (R)-(-)-3-Carbamoymethyl-5-Methylhexanoic Acid
Synonyms (R)-3-(2-Amino-2-Oxoethyl)-5-Methylhexanoic Acid; RCMH; Pregabalin Impurity III 
CAS Number 181289-33-8
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C9H17NO3
Molecular Weight 187.24
Melting Point 126.0~133.0℃
Density 1.080±0.06 g/cm3
COA & MSDS Available
Place of Origin  Shanghai, China
Brand Ruifu Chemical

181289-33-8 - Specifications:

Items Specifications Results
Characteristics White or Off-White Crystalline Powder Conforms
Assay (Titration) More than 99.0% 99.55%
Identification IR & HPLC Conforms
Purity / Analysis Method More than 99.0% (HPLC)  99.71%
Melting Point 126.0~133.0℃ 129.1~131.5℃
S-Isomer Less than 1.00% 0.28%
A-Phenylethylamine Less than 0.50% Conforms
Dicarboxylic Acid Less than 0.30% Conforms
Any Single Impurity Less than 0.50% Conforms
Loss on Drying Less than 1.00% 0.38%
Residue on Ignition Less than 0.30% 0.022%
Test Standard Enterprise Standard Conforms
Usage Intermediate of Pregabalin (CAS: 148553-50-8)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

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181289-33-8 - Application:

(R)-(-)-3-Carbamoymethyl-5-Methylhexanoic Acid (CAS: 181289-33-8) is a useful chemical intermediate for manufacturing of the anticonvulsant drug, Pregabalin (CAS: 148553-50-8). Pregabalin is a new antiepileptic drug, having a γ-amino butyric acid structure on its molecular structure, which has anticonvulsant effects, and is successfully developed by the company Pfizer for the treatment of peripheral neuropathic pain, or adjuvant treatment of partial seizures. Pregabalin is a second- generation antiepileptic drug (AED) known with the proprietary brand name of Lyrica (Pfizer, Tadworth) in the UK and USA (Pfizer, New York, NY).

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