2-(3-Hydroxy-1-Adamantyl)-2-Oxoacetic Acid CAS 709031-28-7 Purity >99.0% (HPLC)

Short Description:

Name: 2-(3-Hydroxy-1-Adamantyl)-2-Oxoacetic Acid

Synonyms: 3-Hydroxy- α-Oxoadamantane-1-Acetic Acid 

CAS: 709031-28-7

Purity: >99.0% (HPLC)  

Appearance: White to Off-White Crystal Powder 

Intermediate of API (CAS: 361442-04-8) 

E-Mail: alvin@ruifuchem.com


Product Detail

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Product Tags

Description:

Chemical Properties:

Chemical Name 2-(3-Hydroxy-1-Adamantyl)-2-Oxoacetic Acid
Synonyms 3-Hydroxy- α-Oxoadamantane-1-Acetic Acid; 3-Hydroxy-Alpha-Oxoadamantane-1-Acetic Acid; 2-​(3-​Hydroxyadamantan-​1-​yl)​-​2-Oxoacetic Acid; 3-Hydroxy-α-Oxotricyclo[3.3.1.13,7]decane-1-Acetic Acid
CAS Number 709031-28-7
CAT Number RF-PI2288
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C12H16O4
Molecular Weight 224.26
Density 1.477
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Off-White Crystal Powder (Visual)
Identification HPLC The Retention Time of Major Peak Obtained from Sample Solution is Correspond to Reference Standard
Melting Point 162.0~166.0℃
Water (by Karl Fischer) <0.50% (USP<921>)
Purity / Analysis Method >99.0% (HPLC) 
Assay  98.0%~102.0% (On Dried Basis)
Test Standard Enterprise Standard
Usage Intermediate of API (CAS: 361442-04-8)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

1

FAQ:

Application:

2-(3-Hydroxy-1-Adamantyl)-2-Oxoacetic Acid (CAS: 709031-28-7) is an intermediate of API (CAS: 361442-04-8), which is a type 2 diabetes drug that can stimulate the pancreas to produce more insulin after the meal. It was reached by the cooperation of AstraZeneca and Bristol-Myers Squibb Company and belongs to DPP-IV inhibitor. It plays the role through inhibiting GLP-l degradation. GLP-I is the hormones naturally produced in the intestine after taking food. It can regulate the secretion of insulin and strengthen the utilization of glucose in the peripheral tissues. 

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