2-Chloroethyl Isocyanate CAS 1943-83-5 Purity >99.0% (GC)

Short Description:

Chemical Name: 2-Chloroethyl Isocyanate

CAS: 1943-83-5

Purity: >99.0% (GC)

Appearance: Colorless to Pale Yellow Clear Liquid

Contact: Dr. Alvin Huang

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E-Mail: alvin@ruifuchem.com

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Product Detail

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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 2-Chloroethyl Isocyanate (CAS: 1943-83-5) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase 2-Chloroethyl Isocyanate, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	2-Chloroethyl Isocyanate
Synonyms	Isocyanic Acid 2-Chloroethyl Ester; 1-Chloro-2-Isocyanatoethane; β-Chloroethylisocyanate; 2-Chloroethanol Isocyanate
Stock Status	In Stock, Commercial Production
CAS Number	1943-83-5
Molecular Formula	C3H4ClNO
Molecular Weight	105.52 g/mol
Boiling Point	135℃
Flash Point	56℃(132°F)
Density	1.237 g/mL at 25℃(lit.)
Refractive Index n20/D	1.447(lit.)
Sensitive	Moisture Sensitive, Heat Sensitive
Water Solubility	Hydrolyzes in Water
Hazard Note	Toxic/Corrosive/Lachrymatory/Sensitizer
COA & MSDS	Available
Sample	Available
Origin	Shanghai, China
Brand	Ruifu Chemical

Specifications:

Items	Inspection Standards	Results
Appearance	Colorless to Pale Yellow Clear Liquid	Colorless Clear Liquid
Purity / Analysis Method	>99.0% (GC)	99.50%
Hydrolyzable Chlorine (as HCl)	<0.50%	0.20%
Refractive Index n20/D	1.444~1.448	Complies
Density (20℃)	1.226~1.237	Complies
Infrared Spectrum	Consistent with Structure	Complies
1H NMR Spectrum	Consistent with Structure	Complies
Conclusion	The product has been tested and complies with the given specifications

Package/Storage/Shipping:

Package: Fluorinated Bottle, 25kg/Drum, 180kg/Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.

1943-83-5 - Stability:

Stable, but moisture sensitive. Combustible. Incompatible with water, moisture, strong oxidizing agents, strong bases, acids, alcohols, amines.

1943-83-5 - Synthetic Route:

2-Chloroethylamine+Triphosgene→2-Chloroethyl Isocyanate Crude Product→Refine→2-Chloroethyl Isocyanate

1943-83-5 - Test Method:

1.0 Instruments and Reagents
Agilent GC-7820A, hydrogen flame detector, chromatography workstation was used for detection and data processing.
2.0 Chromatographic conditions
Column: DB-1 30m×0.32mm×1.0um
N2: 30ml/min
H2: 30ml/min
Air: 300ml/min
Split Ratio: 60:1
Injection volume: 0.2μL
Temperature
50℃ ----5 min ,
Rate: 20℃/min
250℃----10min
Injector Temperature: 250℃
Detector Temperature: 250℃
3.0 Sample Configuration
After the instrument was stabilized, 0.2μL of the sample was sucked directly, injected and analyzed in the split state, the chromatogram was recorded, and quantified by area normalization method.
4.0 Determination of hydrochloric chlorine content
4.1 Methods
4.2. Instruments and Reagents:
AgNO3 standard solution: 0.01 mol/l
Isopropyl Alcohol: analytical purity
Aqueous nitric acid solution: 1:1
Methanol: analytical purity
Sodium hydroxide: analytical purity
Automatic potentiometric titrator
4.3 2M sodium hydroxide in methanol solution
40g of sodium hydroxide solid was weighed, 500ml of methanol was added and dissolved.
4.4 Analysis Steps
Weigh about 2-3 grams of the sample accurately in a 250ml beaker, add 20ml isopropanol to mix, slowly add 15ml sodium hydroxide methanol solution, stir for 10 min, add nitric acid solution (1:1), make the solution PH≤3, and measure with automatic potential titrator.
4.5 Allowable error
The difference between the results of two parallel determinations must not exceed 0.2%

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

1943-83-5 - Safety Information:

Risk Codes
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
R42 - May cause sensitization by inhalation
R34 - Causes burns
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S38 - In case of insufficient ventilation, wear suitable respiratory equipment.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S28A -
S23 - Do not breathe vapour.
S7/9 -
UN IDs UN 1993 3/PG 3
WGK Germany 3
RTECS NQ8450000
FLUKA BRAND F CODES 10-19
TSCA Yes
HS Code 2929109000
Hazard Note Toxic/Corrosive/Lachrymatory/Sensitizer
Hazard Class 6.1
Packing Group II

1943-83-5 - Application:

2-Chloroethyl Isocyanate (CAS: 1943-83-5) is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs. 2-Chloroethyl isocyanate is used as a reagent and building block in chemical synthesis. Synthesis of nitrosourea antitumor drugs.