2-Hydroxy-5-Methylpyridine CAS 1003-68-5 Purity ≥99.0% Pirfenidone Intermediate Factory
Manufacturer Supply, High Purity, Commercial Production
Chemical Name: 2-Hydroxy-5-Methylpyridine
CAS: 1003-68-5
| Chemical Name | 2-Hydroxy-5-Methylpyridine |
| Synonyms | 5-Methyl-2(1H)-Pyridinone; 2-Hydroxy-5-Picoline; 6-Hydroxy-3-Picoline; 5-Methyl-2-Pyridinol |
| CAS Number | 1003-68-5 |
| CAT Number | RF-PI549 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C6H7NO |
| Molecular Weight | 109.13 |
| Melting Point | 183.0 to 187.0℃ (lit.) |
| Solubility | Soluble in Methanol |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | Off-White to Yellow Crystalline Powder |
| Purity | ≥99.0% |
| Moisture Content (K.F) | ≤0.50% |
| Residue on Ignition | ≤0.50% |
| Any Single Impurity | ≤0.50% |
| Total Impurities | ≤1.00% |
| Residual Solvents | |
| n-Butanol | ≤0.30% |
| Ethanol | ≤0.30% |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Pirfenidone (CAS: 53179-13-8) |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture
2-Hydroxy-5-Methylpyridine (CAS: 1003-68-5) is used as a pharmaceutical intermediate of Pirfenidone (CAS: 53179-13-8). Pirfenidone (PFD) is a novel kind of pyridine ketones which has a broad-spectrum anti-fibrotic effect, being able to prevent and reverse the formation of fibrosis and scar. It entered into market in Shionogi, Japan in 2008 and has been approved by the US food and Drug Administration. It is the first drug which has gone through phase III clinical trials (including repeating, randomized, and placebo-control) which has demonstrates its effectiveness in treating idiopathic pulmonary fibrosis (IPF); moreover, the drug has relative good efficacy in treating some fibrotic diseases such as renal interstitial fibrosis and liver fibrosis.
