3-Amino-4-Pyrazolecarboxamide Hemisulfate CAS 27511-79-1 Purity >99.5% (HPLC) Factory

Short Description:

Name: 3-Amino-4-Pyrazolecarboxamide Hemisulfate

Synonyms: 3-Aminopyrazole-4-Carboxamide Hemisulfate; 3-Amino-4-Carbamoylpyrazole Hemisulfate

CAS: 27511-79-1

Purity: >99.5% (HPLC)

Appearance: White to Off-White Powder

Impurity / Intermediate of Allopurinol (CAS: 315-30-0)

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Send email to us

Product Detail

Product Tags

Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 3-Amino-4-Pyrazolecarboxamide Hemisulfate (CAS: 27511-79-1) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	3-Amino-4-Pyrazolecarboxamide Hemisulfate
Synonyms	3-Aminopyrazole-4-Carboxamide Hemisulfate; 3-Amino-4-Carbamoylpyrazole Hemisulfate; 3-Amino-4-Pyrazolecarboxamide Hemisulfate Salt; 3-Amino-1H-Pyrazole-4-Carboxamide Hemisulfate; 3-Amino-Pyrazole-4-Carboxamide Hemisulfate
Impurity	Allopurinol EP Impurity A; Allopurinol USP Related Compound A
CAS Number	27511-79-1
CAT Number	RF2578
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C4H6N4O·1/2H2SO4
Molecular Weight	175.16
Melting Point	224℃(dec.)(lit.)
Density	0.84
Sensitive	Hygroscopic
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White to Off-White Powder
Purity / Analysis Method	>99.5% (HPLC)
Water (by Karl Fischer)	<1.00%
Residue on Ignition	<0.10%
Single Impurity	<0.50%
Total Impurities	<0.50%
Heavy Metals	<20ppm
Infrared Spectrum	Conforms to Structure
Proton NMR Spectrum	Conforms to Structure
Test Standard	Enterprise Standard
Usage	Impurity / Intermediate of Allopurinol (CAS: 315-30-0)

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Excellent quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

Application:

3-Amino-4-Pyrazolecarboxamide Hemisulfate (CAS: 27511-79-1) is a pyrazole derivative, it's an Impurity / Intermediate of Allopurinol (CAS: 315-30-0). Allopurinol is the drug of choice in the treatment of chronic tophaceous gout and is especially useful in patients whose treatment is complicated by renal insufficiency. Allopurinol was synthesized in 1956 as part of a study of purine antagonists. It is well absorbed on oral administration, with peak plasma concentrations appearing within 1 hour. Decreases of uric acid can be observed within 24 to 48 hours. Excretion of allopurinol and its metabolite occurs primarily in the urine, with approximately 20% of a dose being excreted in the feces. Allopurinol does not reduce serum uric acid levels by increasing renal uric acid excretion; instead it lowers plasma urate levels by inhibiting the final steps in uric acid biosynthesis. This action is accomplished by inhibiting xanthine oxidase, the enzyme involved in the metabolism of hypoxanthine and xanthine to uric acid. After enzyme inhibition, the urinary and blood concentrations of uric acid are greatly reduced and there is a simultaneous increase in the excretion of the more soluble uric acid precursors, xanthine and hypoxanthine.