Darunavir Intermediate CAS 102123-74-0 Purity ≥98.0% (HPLC)
Manufacturer Supply Darunavir Related Products:
Darunavir CAS 206361-99-1
Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
| Chemical Name | (3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone |
| Synonyms | (S)-tert-Butyl (4-Chloro-3-oxo-1-Phenylbutan-2-yl)Carbamate |
| CAS Number | 102123-74-0 |
| CAT Number | RF-PI287 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C15H20ClNO3 |
| Molecular Weight | 297.78 |
| Shipping Condition | Shipped Under Ambient Temperature |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | White to Off-White Crystalline Powder |
| Identification (HPLC) | The Identification is Confirmed by HPLC |
| Loss on Drying | ≤0.50% |
| Moisture (K.F) | ≤0.50% |
| Melting Point | 104.0~107.0℃ |
| Residue on Ignition | ≤0.20% |
| Specific Rotation | -48.0° ~ -42.0° |
| Purity / Analysis Method | ≥98.0% (HPLC) |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor |
Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone (CAS: 102123-74-0) with high quality, an intermediate typically in the synthesis of Darunavir (CAS 206361-99-1) and Darunavir Ethanolate (CAS 635728-49-3).
Darunavir (CAS 206361-99-1) (TMC114) is a second generation nonpeptidic HIV protease inhibitor, used to treat AIDS and HIV infection, structurally similar to amprenavir. Antiviral. Due to the emergence of Antiviral drug resistance when used alone, it is administered in combination with other Anti-HIV agents. Darunavir is an orally-bioavailable non-peptidic inhibitor of human immunodeficiency virus type 1 (HIV-1) protease that selectively inhibits HIV-1 protease enzyme induced cleavage of gag and gag-pol poly-proteins preventing the maturation of virions and also inhibits the dimerization of HIV-1 protease suppressing proteolytic activity and subsequent replication of HIV-1.
