4-(Dimethylamino)butyraldehyde Diethyl Acetal CAS 1116-77-4 Purity >98.0% (GC) Zolmitriptan/Sumatriptan Succinate Intermediate

Short Description:

Name: 4-(Dimethylamino)butyraldehyde Diethyl Acetal

Synonyms: 4,4-Diethoxy-N,N-Dimethylbutylamine 

CAS: 1116-77-4

Purity: >98.0% (GC) (T) 

Appearance: Colorless to Pale Yellow Liquid 

Intermediate of Zolmitriptan, Sumatriptan Succinate

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E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 4-(Dimethylamino)butyraldehyde Diethyl Acetal (CAS: 1116-77-4) with high quality. Intermediate for Zolmitriptan (CAS: 139264-17-8), Sumatriptan (CAS: 103628-46-2), Sumatriptan Succinate (CAS: 103628-48-4). We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name 4-(Dimethylamino)butyraldehyde Diethyl Acetal 
Synonyms 4,4-Diethoxy-N,N-Dimethylbutylamine; 4,4-Diethoxy-N,N-Dimethyl-1-Butanamine; 4-Dimethylamino Butanal Diethyl Acetal; N,N-Dimethyl-4-Aminobutanal Diethyl Acetal
Impurity  Zolmitriptan USP Related Compound H 
CAS Number 1116-77-4 
CAT Number RF2662
Stock Status In Stock, Production Capacity 100MT/Year 
Molecular Formula C10H23NO2 
Molecular Weight 189.30  
Boiling Point 194.0~195.0℃
Flash Point 158°F
Density 0.844 g/mL at 25℃(lit.)
Refractive Index n20/D 1.421(lit.)
Sensitive Hygroscopic. Moisture Sensitive 
Solubility  Chloroform, Ethyl Acetate
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Colorless to Pale Yellow Liquid
Purity / Analysis Method >98.0% (GC) 
Purity / Analysis Method 97.5~101.5% (Nonaqueous Titration) 
Total Impurities <2.00%
1 H NMR Spectrum Consistent With Structure 
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediate; Zolmitriptan, Sumatriptan Succinate

Package & Storage:

Package: Fluorinated Bottle, 25kg/Barrel, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

4-(Dimethylamino)butyraldehyde Diethyl Acetal (CAS: 1116-77-4) is used in organic synthesis and pharmaceutical intermediates, it is an intermediate for Zolmitriptan (CAS: 139264-17-8), Sumatriptan (CAS: 103628-46-2), Sumatriptan Succinate (CAS: 103628-48-4), Rizatriptan (CAS: 144034-80-0), Almotriptan (CAS: 154323-57-6). Zolmitriptan is a selective serotonin receptor agonist of the 1B and 1D subtypes. It is mainly used in the acute treatment of migraine attacks with or without aura and cluster headaches. Zolmitriptan takes effect through binding to human 5-HT1Band 5-HT1Dreceptors, leading to cranial blood vessel constriction and the release of sensory neuropeptides through nerve endings in the trigeminal system. Sumatriptan Succinate is a synthetic drug belonging to a class of medications known as 5-hydroxytryptamine agonists (also called "triptans"), which is commonly used to treat cluster and migraine headaches with or without aura (warning signs occurring prior to the onset of a migraine). Sumatriptan Succinate is effective to relieve or eliminate the intensity of migraine and cluster headaches and accompanying symptoms including sensitivity to light or sound, nausea, and vomiting. However, Sumatriptan Succinate cannot help prevent future migraines/headaches or decrease the frequency of getting migraine and it is not recommended for other types of headache or for headache prevention.

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