4-Phenoxyphenylboronic Acid CAS 51067-38-0 Ibrutinib Intermediate Purity >99.0% (HPLC)

Short Description:

Chemical Name: 4-Phenoxyphenylboronic Acid 

CAS: 51067-38-0

Purity: >99.0% (HPLC)

Appearance: White to Off-White Powder 

Intermediate of Ibrutinib (CAS: 936563-96-1) 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401    

E-Mail: alvin@ruifuchem.com


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Description:

Chemical Properties:

Chemical Name 4-Phenoxyphenylboronic Acid
Synonyms 4-Phenoxybenzeneboronic Acid
CAS Number 51067-38-0
CAT Number RF-PI1283
Stock Status In Stock, Production Scale Up to 25 Tons/Month
Molecular Formula C12H11BO3
Molecular Weight 214.03 
Melting Point 141.0~145.0℃ (lit.)
Solubility Soluble in Methanol
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White Powder
Purity / Analysis Method >99.5% (HPLC)
Loss on Drying <0.50%
Residue on Ignition <0.30%
Single Impurity <0.50%
Total Impurities <0.50%
Heavy Metals (as Pb) <20ppm
Infrared Spectrum Conforms to Structure
Proton NMR Spectrum Conforms to Structure
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediates; Intermediate of Ibrutinib (CAS: 936563-96-1)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

Advantages:

1

FAQ:

Application:

4-Phenoxyphenylboronic Acid (CAS: 51067-38-0) is a kind of chemical intermediates with a wide range of applications, widely used in the synthesis of pharmaceuticals, dyes and other fine chemical products. It's an intermediate of anticancer drugs, such as Ibrutinib (CAS: 936563-96-1). Ibrutinib is a kind of Bruton tyrosine kinase (BTK) inhibitor, it could be used for the treatment of chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). 4-Phenoxyphenylboronic Acid can be used as a reactant: In the Suzuki-Miyaura coupling reaction to synthesize aryl derivatives via C-C bond formation by reacting with different aryl halides over a palladium catalyst.

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