4-Phenoxyphenylboronic Acid CAS 51067-38-0 Ibrutinib Intermediate Purity >99.0% (HPLC)
Chemical Name | 4-Phenoxyphenylboronic Acid |
Synonyms | 4-Phenoxybenzeneboronic Acid |
CAS Number | 51067-38-0 |
CAT Number | RF-PI1283 |
Stock Status | In Stock, Production Scale Up to 25 Tons/Month |
Molecular Formula | C12H11BO3 |
Molecular Weight | 214.03 |
Melting Point | 141.0~145.0℃ (lit.) |
Solubility | Soluble in Methanol |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White Powder |
Purity / Analysis Method | >99.5% (HPLC) |
Loss on Drying | <0.50% |
Residue on Ignition | <0.30% |
Single Impurity | <0.50% |
Total Impurities | <0.50% |
Heavy Metals (as Pb) | <20ppm |
Infrared Spectrum | Conforms to Structure |
Proton NMR Spectrum | Conforms to Structure |
Test Standard | Enterprise Standard |
Usage | Pharmaceutical Intermediates; Intermediate of Ibrutinib (CAS: 936563-96-1) |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
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4-Phenoxyphenylboronic Acid (CAS: 51067-38-0) is a kind of chemical intermediates with a wide range of applications, widely used in the synthesis of pharmaceuticals, dyes and other fine chemical products. It's an intermediate of anticancer drugs, such as Ibrutinib (CAS: 936563-96-1). Ibrutinib is a kind of Bruton tyrosine kinase (BTK) inhibitor, it could be used for the treatment of chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). 4-Phenoxyphenylboronic Acid can be used as a reactant: In the Suzuki-Miyaura coupling reaction to synthesize aryl derivatives via C-C bond formation by reacting with different aryl halides over a palladium catalyst.
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