4,6-Dichloro-2-Methylpyrimidine CAS 1780-26-3 Purity ≥99.5% (GC) Factory Hot Sale

Short Description:

Chemical Name: 4,6-Dichloro-2-Methylpyrimidine

CAS: 1780-26-3

Purity: ≥99.5% (GC)

Appearance: White or Off-White Crystalline Powder

High Quality, Commercial Production

Intermediate of Dasatinib / Moxonidine

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 4,6-Dichloro-2-Methylpyrimidine (CAS: 1780-26-3) with high quality, commercial production. We can provide COA, worldwide delivery, small and bulk quantities available. Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	4,6-Dichloro-2-Methylpyrimidine
Synonyms	2-Methyl-4,6-Dichloropyrimidine; 2,4-Dichloro-6-Methylpyrimidine
CAS Number	1780-26-3
CAT Number	RF-PI687
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C5H4Cl2N2
Molecular Weight	163.00
Melting Point	41.5~45.5℃ (lit.)
Solubility (Soluble in)	Methanol
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White or Off-White Crystalline Powder
Purity / Analysis Method	≥99.5% (GC)
Loss on Drying	≤0.50%
Residue on Ignition	≤0.20%
Single Impurity	≤0.50%
Total Impurities	≤0.50%
Test Standard	Enterprise Standard
Usage	Pharmaceutical Intermediate; Dasatinib/Moxonidine Intermediate

4,6-Dichloro-2-Methylpyrimidine (CAS: 1780-26-3) Process Route

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

FAQ:

Application:

4,6-Dichloro-2-Methylpyrimidine (CAS: 1780-26-3) is used in the synthesis of pharmaceutical intermediates and APIs. Preparation Products: Moxonidine (CAS: 75438-57-2); Dasatinib (CAS: 302962-49-8); Dasatinib Monohydrate (CAS: 863127-77-9); 4-Chloro-2,6-Dimethylpyrimidine (CAS: 4472-45-1); 4-Amino-6-Chloro-2-Methylpyrimidine (CAS: 1749-68-4). Moxonidine is a new type of antihypertensive drug, commonly used in the treatment of essential hypertension. Compared to the older central-acting antihypertensives, Moxonidine binds with much greater affinity to the imidazoline I1-receptor than to the α2-receptor. Dasatinib is an oral potent oncogenic kinase inhibitor, which can block signal of cancer cell replication acceleration , in May 2009, the US Food and Drug Administration (FDA) formally approved the sale of dasatinib , It has been clinically used for the treatment of various chronic myeloid leukemia (CML), including treatment of chronic myeloid leukemia which is resistant or intolerant to the treating programs including imatinib mesylate., Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph + ALL) and the treatment of patients with solid tumors.