5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8 Purity >99.0% (HPLC) Palbociclib Intermediate Factory

Short Description:

5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine 

CAS: 733039-20-8

Purity: >99.0% (HPLC) 

Appearance: White to Off-White Powder

Intermediate of Palbociclib (CAS: 571190-30-2)

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com


Product Detail

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Description:

Chemical Properties:

Chemical Name 5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine
Synonyms N-(5-Bromo-2-Chloropyrimidin-4-yl)(cyclopentyl)amine; 5-Bromo-2-Chloro-4-(Cyclopentylamino)pyrimidine
CAS Number 733039-20-8
CAT Number RF-PI1851
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C9H11BrClN3
Molecular Weight 276.56
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Off-White Powder
Purity / Analysis Method >99.0% (HPLC)    
1 H NMR Spectrum Consistent With Structure
Loss on Drying <1.00%
Total Impurities <1.00%
Test Standard Enterprise Standard
Usage Intermediate of Palbociclib (CAS: 571190-30-2)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

1

FAQ:

Application:

5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine (CAS: 733039-20-8) can be used as an intermediate of Palbociclib (CAS: 571190-30-2). Palbociclib (trade name: Ibrance) is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Palbociclib is a kinase inhibitor indicated for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in combination with: An aromatase inhibitor as initial endocrine based therapy in postmenopausal women; or Fulvestrant in women with disease progression following endocrine therapy.

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