5-Chloro-1-Methyl-4-Nitroimidazole CAS 4897-25-0 Purity ≥99.5% (HPLC) Azathioprine Intermediate Factory

Short Description:

Chemical Name: 5-Chloro-1-Methyl-4-Nitroimidazole 

CAS: 4897-25-0

Purity: ≥99.5% (HPLC)

Appearance: White or Off-White Crystalline Powder

Intermediate of Azathioprine (CAS: 446-86-6)

High Quality, Commercial Production

E-Mail: alvin@ruifuchem.com


Product Detail

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Description:

Manufacturer Supply, High Purity, Commercial Production
Azathioprine Related Intermediates
5-Chloro-1-Methyl-4-Nitroimidazole CAS 4897-25-0
6-Mercaptopurine CAS 50-44-2

Chemical Properties:

Chemical Name 5-Chloro-1-Methyl-4-Nitroimidazole
Synonyms 5-Chloro-1-Methyl-4-Nitro-Imidazol; 5-Chloro-1-Methyl-4-Nitro-1H-Imidazole; 1-Methyl-5-Chloro-4-Nitroimidazole; Azathioprine EP Impurity C; CMNI
CAS Number 4897-25-0
CAT Number RF-PI957
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C4H4ClN3O2  
Molecular Weight 161.55  
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White or Off-White Crystalline Powder
Identification IR Conform to Standard 
Melting Point 147.0~150.0℃
Loss on Drying ≤0.50%
Residue on Ignition ≤0.20%
Individual Impurity ≤0.20%
Total Impurities ≤0.50%
Purity / Analysis Method  ≥99.5% (HPLC)
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediate; Intermediate of Azathioprine (CAS 446-86-6)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

Advantages:

1

FAQ:

Application:

5-Chloro-1-Methyl-4-Nitroimidazole (CAS: 4897-25-0) is an imidazole derivative. 5-Chloro-1-methyl-4-nitroimidazole is an intermediate in Azathioprine (CAS: 446-86-6) synthesis, also present in the end product. Cross reactivity is possible with imidazoles tioconazole, and econazole. 5-Chloro-1-methyl-4-nitroimidazole can be condensed with 6- Mercaptopurine (CAS: 50-44-2) to obtain Azathioprine. Azathioprine is an immunosuppressant which is commonly used in organ transplantation, autoimmune disease or Inflammatory Bowel Disease (IBD).  It is also used in multiple sclerosis, autoimmune hepatitis and restrictive lung disease.  It's also active as disease modifying antirheumatic drug (DMARD). An immunosuppressive antimetabolite that interferes with the synthesis of purines. Ruifu Chemical can supply both 5-Chloro-1-Methyl-4-Nitroimidazole and 6- Mercaptopurine.

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