5-Chloro-1-Methyl-4-Nitroimidazole CAS 4897-25-0 Purity ≥99.5% (HPLC) Azathioprine Intermediate Factory
Manufacturer Supply, High Purity, Commercial Production
Azathioprine Related Intermediates
5-Chloro-1-Methyl-4-Nitroimidazole CAS 4897-25-0
6-Mercaptopurine CAS 50-44-2
Chemical Name | 5-Chloro-1-Methyl-4-Nitroimidazole |
Synonyms | 5-Chloro-1-Methyl-4-Nitro-Imidazol; 5-Chloro-1-Methyl-4-Nitro-1H-Imidazole; 1-Methyl-5-Chloro-4-Nitroimidazole; Azathioprine EP Impurity C; CMNI |
CAS Number | 4897-25-0 |
CAT Number | RF-PI957 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C4H4ClN3O2 |
Molecular Weight | 161.55 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White or Off-White Crystalline Powder |
Identification | IR Conform to Standard |
Melting Point | 147.0~150.0℃ |
Loss on Drying | ≤0.50% |
Residue on Ignition | ≤0.20% |
Individual Impurity | ≤0.20% |
Total Impurities | ≤0.50% |
Purity / Analysis Method | ≥99.5% (HPLC) |
Test Standard | Enterprise Standard |
Usage | Pharmaceutical Intermediate; Intermediate of Azathioprine (CAS 446-86-6) |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
5-Chloro-1-Methyl-4-Nitroimidazole (CAS: 4897-25-0) is an imidazole derivative. 5-Chloro-1-methyl-4-nitroimidazole is an intermediate in Azathioprine (CAS: 446-86-6) synthesis, also present in the end product. Cross reactivity is possible with imidazoles tioconazole, and econazole. 5-Chloro-1-methyl-4-nitroimidazole can be condensed with 6- Mercaptopurine (CAS: 50-44-2) to obtain Azathioprine. Azathioprine is an immunosuppressant which is commonly used in organ transplantation, autoimmune disease or Inflammatory Bowel Disease (IBD). It is also used in multiple sclerosis, autoimmune hepatitis and restrictive lung disease. It's also active as disease modifying antirheumatic drug (DMARD). An immunosuppressive antimetabolite that interferes with the synthesis of purines. Ruifu Chemical can supply both 5-Chloro-1-Methyl-4-Nitroimidazole and 6- Mercaptopurine.