6-Carboxyfluorescein (6-FAM) CAS 3301-79-9 Purity >97.0% (HPLC)

Short Description:

Chemical Name: 6-Carboxyfluorescein

Synonyms: 6-FAM 

CAS: 3301-79-9

Purity: >97.0% (HPLC)

Appearance: Yellow to Orange Powder

Fluorescent Labeling Dyes, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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3301-79-9 - Description:

Ruifu Chemical is the leading manufacturer of 6-Carboxyfluorescein (6-FAM) (CAS: 3301-79-9) with high quality, fluorescent labeling dyes. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase 6-Carboxyfluorescein, Please contact: alvin@ruifuchem.com

3301-79-9 - Chemical Properties:

Chemical Name 6-Carboxyfluorescein 
Synonyms 6-FAM; 6-Carboxyfluorescein Hydrate; 3',6'-Dihydroxy-1-Oxospiro[2-Benzofuran-3,9'-Xanthene]-5-Carboxylic Acid
Stock Status In Stock, Commercial Production  
CAS Number 3301-79-9
Molecular Formula C21H12O7
Molecular Weight 376.32 g/mol
Melting Point >300℃(lit.) 
Density 1.73±0.10 g/cm3 
Sensitive Light Sensitive 
COA & MSDS Available
Place of Origin  Shanghai, China
Product Categories
Fluorescent Labeling Dyes  
Brand Ruifu Chemical

3301-79-9 - Specifications:

Items Specifications  Results
Appearance Yellow to Orange Powder  Complies      
Purity / Analysis Method >97.0% (HPLC)  98.97% 
1H NMR Spectrum Consistent with Structure Complies
MS Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications

3301-79-9 - Analysis Method:

Description Visual Inspection Conforms 
Identity 1H NMR, MS Conforms 
Purity by HPLC >97.0%  98.97%
Column XDB-C18
Flow Rate 0.8mL/min 
Detection UV at 254 nm C
HPLC Elution Buffer CH3CN: 0.1%TFA=35:65 

Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

3301-79-9 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes
36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
WGK Germany 3
FLUKA BRAND F CODES 10-21
HS Code 3204 9010.00

3301-79-9 - Application:

6-Carboxyfluorescein (6-FAM) (CAS: 3301-79-9) is used as fluorescent labeling dyes, fluorescent labelling reagent. Used for nucleic acid sequencing and labeling.
6-Carboxyfluorescein is derivative of fluorescein giving stable derivative upon conjugation with biopolymers.
6-Carboxyfluorescein contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid. Fluorescein is the most common fluorescent derivatization reagent for labeling biomolecules. In addition to its relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility, fluorescein has an excitation maximum that closely matches the 488 nm spectral line of the argon-ion laser.
6-Carboxyfluorescein is a useful reagent for the preparation of hydrolytically stable fluorescent conjugates and is a useful starting material for the synthesis of other fluorescein-derived reagents. Dyes and metabolites.
6-Carboxyfluorescein diacetate is a membrane permeable compound. It can be hydrolysed by intracellular esterases to form a membrane impermeable bright green fluorescent molecule.

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