7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2 Purity >99.5% (HPLC) Agomelatine Intermediate Factory

7-Methoxy-1-Naphthaleneacetic Acid (CAS: 6836-22-2) is an intermediate of Agomelatine (CAS: 138112-76-2). Agomelatine is an antidepressant used to treat depression. The brain is usually good at making sure we have enough of the chemicals we need to function properly. But depression can affect a number of brain chemicals. These chemicals include noradrenaline, dopamine and serotonin; depression reduces levels of these brain transmitters. Depression also affects a chemical called melatonin. Reduced melatonin is linked to disturbances in our sleep patterns. Agomelatine is the first antidepressant to increase melatonin activity directly. It does this by acting like melatonin at the target sites where melatonin works. (These are known as the melatonin receptors). By increasing melatonin activity, agomelatine also directly increases activity of noradrenaline and dopamine. Agomelatine has some anti-anxiety effects, relieves insomnia in people with depression. Agomelatine regulates the body's sleep-wake cycle. Agomelatine is a breakthrough in the treatment of depression. Agomelatine is developed by the pharmaceutical company Servier. It is marketed for the treatment of major depressive disorder and has been reported to not produce discontinuation syndrome and have no sexual side effects compared to SSRIs, SNRIs and the older tricyclic antidepressants. Agomelatine may also have positive effects on sleep.