Acetylcholine Chloride CAS 60-31-1 Assay 98.0~102.0%

Short Description:

Chemical Name: Acetylcholine Chloride

Synonyms: ACh Chloride 

CAS: 60-31-1

Assay: 98.0~102.0%

Appearance: White to Off-White Crystalline Powder

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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60-31-1 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Acetylcholine Chloride (ACh Chloride) (CAS: 60-31-1) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Acetylcholine Chloride, Please contact: alvin@ruifuchem.com

60-31-1 - Chemical Properties:

Chemical Name Acetylcholine Chloride
Synonyms ACh Chloride; 2-Acetoxy-N,N,N-Trimethylethanium Chloride; 2-(Acetyloxy)-N,N,N-Trimethylethanaminium Chloride; 2-Acetoxyethyltrimethylammonium Chloride; N-(2-Hydroxyethyl)trimethylammonium Chloride Acetate
Stock Status In Stock, Commercial Production  
CAS Number 60-31-1
Molecular Formula C7H16ClNO2
Molecular Weight 181.66 g/mol
Melting Point 149.0~152.0℃ 
Sensitive Light Sensitive, Very Hygroscopic. Store Under Argon
Water Solubility  Completely Soluble in Water, Almost Transparency
Solubility  Very Soluble in Alcohol. Insoluble in Ether
Stability Stable. Substances to be Avoided Include Strong Oxidizing Agents. Protect From Moisture - Very Hygroscopic.
COA & MSDS Available
Sample  Available
Origin Shanghai, China
Brand Ruifu Chemical

60-31-1 - Specifications:

Items Specifications  Results
Appearance White to Off-White Crystalline Powder White Crystalline Powder
Melting Point 149.0~152.0℃ 149.0~151.0℃
Loss on Drying <1.00% (105℃ for 3 Hours) 0.45%
Residue on ignition <0.20% <0.20%
Chloride Content (Cl) 19.3%~19.8% Complies  
Assay (Argentometric Titration) 98.0~102.0% (on Anhydrous Substance)  99.31%
Infrared Spectrum  Conforms to Structure  Complies  
1H NMR Spectrum Conforms to Structure  Complies  
Solubility in H2O 0.4g/4ml Water Clear Colorless    Pass  
Conclusion The product has been tested and complies with the given specifications  
Shelf Life 2 Years When Properly Stored 

Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Very Hygroscopic. Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Keep away from strong, direct light. Store away from moisture. Store under dry inert gas. Incompatible with heat, oxidizing agents.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

60-31-1 - USP35 Standard:

Acetylcholine Chloride
C7H16ClNO2 181.66
Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride.
Choline acetate (ester) chloride [60-31-1].
Acetylcholine Chloride contains not less than 98.0 percent and not more than 102.0 percent of C7H16 ClNO2, calculated on the dried basis.
Packaging and storage- Preserve in tight container, and store at controlled room temperature.
USP Reference standards <11>-
USP Acetylcholine Chloride RS Click to View Structure
Identification-
A: Infrared Absorption <197K>.
B: To 5 mL of a solution (1 in 10) add 5 mL of silver nitrate TS: a white, curdy precipitate, which is soluble in ammonium hydroxide but insoluble in nitric acid, is formed.
Melting range, Class I <741>: between 149 and 152.
Acidity-Dissolve 100 mg in 10 mL of recently boiled water, and add at once 1 drop of bromothymol blue TS: not more than 0.50 mL of 0.010 N sodium hydroxide is required in order to produce a color change.
Loss on drying <731>-Dry it at 105 for 3 hours: it loses not more than 1.0% of its weight.
Residue on ignition <281>: not more than 0.2%.
Chloride content- Transfer about 280 mg, accurately weighed, to a porcelain casserole, and add 140 mL of water and 1 mL of dichlorofluorescein TS. Mix, and titrate with 0.1 N silver nitrate VS until the silver chloride flocculates and the mixture acquires a faint pink color. Each mL of 0.1 N silver nitrate is equivalent to 3.545 mg of Cl. Not less than 19.3% and not more than 19.8% of Cl, calculated on the dried basis, is found.
Assay-Weigh accurately about 400 mg of Acetylcholine Chloride, and dissolve in 15 mL of water in a glass-stoppered conical flask. Add 40.0 mL of 0.1 N sodium hydroxide VS, and heat on a steam bath for 30 minutes. Insert the stopper, allow to cool, add phenolphthalein TS, and titrate the excess alkali with 0.1 N sulfuric acid VS. Perform a blank determination (see Residual Titrations under Titrimetry 541). Each mL of 0.1 N sodium hydroxide is equivalent to 18.17 mg of C7H16ClNO2.  

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

60-31-1 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
S36 - Wear suitable protective clothing.
WGK Germany 2
RTECS FZ9800000
FLUKA BRAND F CODES 3-8-10-21
TSCA Yes
HS Code 2923100000
Hazard Class IRRITANT

60-31-1 - Precautionary Statements:

P264: Wash skin thoroughly after handling.
P280: Wear protective gloves/ eye protection/ face protection.
P337 + P313: If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P362: Take off contaminated clothing and wash before reuse.

60-31-1 - Application:

Acetylcholine Chloride (ACh Chloride) (CAS: 60-31-1) is a neurotransmitter, is a potent cholinergic agonist. Cholinergic, antiarrhythmic, miotic, vasodilator (peripheral). Endogenous neurotransmitter at cholinergic synapses; amplifies sarcolemma action potential inducing muscle contractions. A cholinergic neurotransmitter that can induce the opening of calcium channels. The chloride salt of acetylcholine, and a parasympatomimetic drug. Acetylcholine Chloride is used as a substrate for the determination of acetylcholinesterase; Clinically as a cholinergic drug.

60-31-1 - Biological Activity:

Compound Acetylcholine Chloride is a neurotransmitter, acts on the peripheral nervous system (PNS) and central nervous system (CNS) of many organisms, including humans. 

60-31-1 - Acetylcholine Chloride for Ophthalmic Solution:

Acetylcholine Chloride for Ophthalmic Solution is a sterile mixture of Acetylcholine Chloride with Mannitol or other suitable diluent, prepared by freeze-drying. Each container contains not less than 90.0 percent and not more than 115.0 percent of the labeled amount of acetylcholine chloride (C7H16ClNO2). Acetylcholine Chloride is a hygroscopic powder that is available inan admixture with mannitol to be dissolved in sterile waterfor injection shortly before use. It is a short-acting mioticwhen introduced into the anterior chamber of the eye and isespecially useful after cataract surgery during the placementof sutures.  

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