Boc-cis-Hyp-OMe CAS 102195-79-9 Purity >98.5% (HPLC) Factory

Short Description:

N-Boc-cis-4-Hydroxy-L-Proline Methyl Ester  

Synonyms: Boc-cis-Hyp-OMe

CAS: 102195-79-9  

Purity: >98.5% (HPLC) 

Appearance: White to Off-White Powder  

Amino Acids and Derivative, High Quality 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of N-Boc-cis-4-Hydroxy-L-Proline Methyl Ester (Boc-cis-Hyp-OMe) (CAS: 102195-79-9) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide worldwide delivery, small and bulk quantities available. Purchase Boc-cis-Hyp-OMe, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name N-Boc-cis-4-Hydroxy-L-Proline Methyl Ester  
Synonyms Boc-cis-Hyp-OMe; N-(tert-Butoxycarbonyl)-cis-4-Hydroxy-L-Proline Methyl Ester; (2S,4S)-4-Hydroxypyrrolidine-1,2-Dicarboxylic Acid 1-tert-Butyl 2-Methyl Ester; 1-tert-Butyl 2-Methyl (2S,4S)-4-Hydroxypyrrolidine-1,2-Dicarboxylate
Stock Status In Stock 
CAS Number 102195-79-9  
Molecular Formula C11H19NO5
Molecular Weight 245.28 g/mol
Melting Point 82.0~86.0℃(lit.) 
Boiling Point 335.2±42.0℃
Density 1.216±0.06 g/cm3 
Sensitive Hygroscopic 
Water Solubility  Insoluble in Water 
Storage Temp.  Sealed in Cool & Dry Place (2~8℃) 
COA & MSDS Available
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance White to Off-White Powder  White Powder 
Melting Point 82.0~86.0℃ Complies 
Specific Rotation [α]20/D -63.0° to -67.0° (C=1 in MeOH)
-65.42°
Loss on Drying <0.50% 0.43% 
Boc-cis-Hyp-OMe Purity  >98.5% (HPLC)  98.91% 
Infrared Spectrum Conforms to Structure Complies      
Proton NMR Spectrum Conforms to Structure Complies      
Conclusion This Product by Inspection Accords with the Enterprise Standard
Main Uses Peptide Synthesis; Pharmaceutical Intermediates; etc.

Package & Storage:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

102195-79-9 - Risk and Safety:

Hazard Symbols Xn - Harmful
Risk Codes
R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
R43 - May cause sensitization by skin contact
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
WGK Germany 2
HS Code 2922491990

Application:

N-Boc-cis-4-Hydroxy-L-Proline Methyl Ester (Boc-cis-Hyp-OMe) (CAS: 102195-79-9), amino acids and derivatives, peptide synthesis, used as amino acid protective monomer, organic synthesis intermediate, pharmaceutical intermediates, biochemical reagents, chemical reagents. Employed as important intermediates in various areas such as peptide synthesis, polymer chemistry. Boc-cis-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-cis-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

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