Boc-Hyp-OMe CAS 74844-91-0 N-Boc-trans-4-Hydroxy-L-Proline Methyl Ester Purity >99.0% (HPLC) Factory

Short Description:

N-Boc-trans-4-Hydroxy-L-Proline Methyl Ester

Synonyms: Boc-Hyp-OMe; Boc-L-Hyp-OMe

CAS: 74844-91-0

Purity: >99.0% (HPLC)

Appearance: White Powder

Unnatural Amino Acids, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of N-Boc-trans-4-Hydroxy-L-Proline Methyl Ester (Boc-Hyp-OMe) (CAS: 74844-91-0) with high quality. Ruifu Chemical supplys a series of amino acids. We can provide worldwide delivery, small and bulk quantities available. Purchase Boc-Hyp-OMe , Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	N-Boc-trans-4-Hydroxy-L-Proline Methyl Ester
Synonyms	Boc-Hyp-OMe; Boc-L-Hyp-OMe; Boc-L-trans-4-Hydroxyproline Methyl Ester; Boc-L-Hydroxyproline Methyl Ester; N-(tert-Butoxycarbonyl)-trans-4-Hydroxy-L-Proline Methyl Ester; 1-tert-Butyl 2-Methyl (2S,4R)-4-Hydroxypyrrolidine-1,2-Dicarboxylate; (2S,4R)-4-Hydroxypyrrolidine-1,2-Dicarboxylic Acid 1-tert-Butyl 2-Methyl Ester; Boc-(2S,4R)-4-Hydroxypyrrolidine-2-Carboxylic Acid Methyl Ester
Stock Status	In Stock
CAS Number	74844-91-0
Molecular Formula	C11H19NO5
Molecular Weight	245.28 g/mol
Melting Point	92.0~96.0℃
Boiling Point	132℃/0.05 mmHg
Density	1.216
Solubility	Soluble in Chloroform, Dichloromethane and Ethyl Acetate
Storage Temp.	Cool & Dry Place (≤25℃)
COA & MSDS	Available
Category	Unnatural Amino Acids
Brand	Ruifu Chemical

Specifications:

Items	Inspection Standards	Results
Appearance	White Powder	White Powder
Melting Point	92.0~96.0℃	92.0~96.0℃
Specific Rotation [α]20/D	-63.0° to -67.0° (C=1, CHCl3)	-63.9°
Loss on Drying	<0.50%	0.23%
Purity / Analysis Method	>99.0% (HPLC)	99.18%
Clarity of Solution	0.3 gram in 2ml DMF Clear Solution	Complies
Mass Spectrum	In Accordance With the Standard	Complies
NMR Spectrum	In Accordance With the Standard	Complies
Conclusion	This Product by Inspection Accords with the Enterprise Standard
Main Uses	Peptide Synthesis; Pharmaceutical Intermediates； etc.

74844-91-0 - Risk and Safety:

Hazard Symbols Xn - Harmful
Risk Codes R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S24/25 - Avoid contact with skin and eyes.
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
HS Code 2922491990
Hazard Class IRRITANT

Package & Storage:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool, dry (≤25℃) and ventilated warehouse away from incompatible substances. Protect from light and moisture.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

Application:

N-Boc-trans-4-Hydroxy-L-Proline Methyl Ester (Boc-Hyp-OMe) (CAS: 74844-91-0), amino acids and derivatives, peptide synthesis, used as amino acid protective monomer, organic synthesis intermediate, pharmaceutical intermediates, biochemical reagents, chemical reagents.
Boc-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.