Boc-L-Threonine CAS 2592-18-9 (Boc-Thr-OH) Purity >99.0% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Boc-L-Threonine (Boc-Thr-OH) (CAS: 2592-18-9) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide worldwide delivery, small and bulk quantities available. Purchase Boc-Thr-OH, Please contact: alvin@ruifuchem.com
| Chemical Name | Boc-L-Threonine |
| Synonyms | Boc-Thr-OH; Boc-L-Thr-OH; N-Boc-L-Threonine; N-(tert-Butoxycarbonyl)-L-Threonine |
| Stock Status | In Stock |
| CAS Number | 2592-18-9 |
| Molecular Formula | C9H17NO5 |
| Molecular Weight | 219.24 g/mol |
| Melting Point | 55.0~85.0℃ |
| Density | 1.202 |
| Storage Temp. | Cool & Dry Place (0~8℃) |
| COA & MSDS | Available |
| Category | Boc-Amino Acids |
| Brand | Ruifu Chemical |
| Hazard Codes | Xn | WGK Germany | 3 |
| Risk Statements | 20/21/22-36/37/38 | HS Code | 2922491990 |
| Safety Statements | 24/25-36-26 |
| Items | Inspection Standards | Results |
| Appearance | White Powder | White Powder |
| Melting Point | 55.0~85.0℃ | 55.1~57.3℃ |
| Specific Rotation [α]20/D | -9.0° ± 1.0° (C=2 in AcOH) |
-8.4° |
| Water Content (K.F.) | <2.0% | 1.2% |
| Ignition Residue (as Sulfate) | <0.20% | 0.11% |
| Element Analysis (C、H、N) | ≤5.0% | <5.0% |
| Boc-Thr-OH Purity | >99.0% (HPLC) | 99.31% |
| TLC | ≥98.0% | >98.0% |
| Clarity of Solution | 0.3 gram in 2ml EtOH Clear Solution | Complies |
| Mass Spectrum | In Accordance With the Standard | Complies |
| NMR Spectrum | In Accordance With the Standard | Complies |
| Conclusion | This Product by Inspection Accords with the Enterprise Standard | |
| Main Uses | Boc-Amino Acids; Peptide Synthesis; Pharmaceutical Intermediates | |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry (0~8℃) warehouse away from incompatible substances. Protect from light and moisture.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Boc-L-Threonine (Boc-Thr-OH) (CAS: 2592-18-9), amino acids and derivatives, peptide synthesis, organic synthesis intermediate, pharmaceutical intermediates, biochemical reagents. Boc-L-Threonine is mainly used in polypeptide synthesis, mainly used in a variety of drugs and biotechnology applications. Threonine has a wide range of uses and functions. In the prior art, Boc is used as a protecting group to protect L-Threonine. Boc-L-Threonine is an important intermediate raw material for many kinds of medicine and biotechnology.
Preparation 1. add 15.8gL-threonine, add 200ml of 0.0005mol/L potassium bicarbonate solution, stir and dissolve, then add 8g of (Boc)2O for reaction for 2 hours, then add 8g of (Boc)2O for reaction for 2 hours, and finally add 9g of (Boc)2O for reaction for 2 hours. 2. After adjusting PH = 3 with 0.001mol/L hydrochloric acid, use tert-butyl acetate 0.4L/time to extract the product three times. Combine ester layers and wash with brine to neutral. Add 15 grams of anhydrous sodium sulfate and dry for 8 hours. 3. Filter, concentrate and dry the filtrate under reduced pressure, add 50ml petroleum ether, stir and crystallize. Centrifuge out the product and dry it. The product 22.4g is obtained. The yield is 91.73%.
