BOP Reagent CAS 56602-33-6 Peptide Coupling Reagent Purity >99.0% (HPLC) Factory

Short Description:

Chemical Name: BOP Reagent

CAS: 56602-33-6

Purity: >99.0% (HPLC)

Appearance: White Crystalline Powder

Coupling Reagent for Peptide, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of BOP Reagent (CAS: 56602-33-6) with high quality. Ruifu Chemical supplys a series of protecting reagents and coupling reagents. Ruifu can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase BOP Reagent, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	BOP Reagent
Synonyms	BOP; Castro’s Reagent; 1H-Benzotriazol-1-yloxytris(dimethylamino) phosphonium Hexafluorophosphate; (Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium Hexafluorophosphate; Benzotriazol-1-yl-oxy-tris(dimethylamino)phosphonium Hexafluorophosphate
Stock Status	In Stock, Mass Production
CAS Number	56602-33-6
Molecular Formula	C12H22F6N6OP2
Molecular Weight	442.29 g/mol
Melting Point	135.0°~140.0℃
Sensitive	Light Sensitive, Moisture Sensitive. Store Under Nitrogen
Solubility	Soluble in Methanol, Acetone and Dichloromethane
Storage Temp.	Cool & Dry Place (≤-20℃)
COA & MSDS	Available
Category	Coupling Reagents
Brand	Ruifu Chemical

Specifications:

Items	Inspection Standards	Results
Appearance	White Crystalline Powder	Complies
Melting Point	135.0°~140.0℃	136.4~138.5℃
Loss on Drying	<0.50%	0.08%
Heavy Metals (Pb)	≤20ppm	<20ppm
Purity / Analysis Method	>99.0% (HPLC)	99.85%
Solution Test (in DMF)	Clear & Transparent	Clear & Transparent
Infrared Spectrum	Conforms to Structure	Complies
NMR Spectrum	Conforms to Structure	Complies
Conclusion	The product has been tested & complies with the given specifications
Attention	Protect from the light and store in a cool and dry place (≤-20℃)

Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Moisture and light sensitive. Store in sealed containers at cool and dry (≤-20℃) warehouse away from incompatible substances. Protect from light and moisture. Incompatible with strong oxidizing agents.
Shipping: Deliver to worldwide by FedEx / DHL Express. Provide fast and reliable delivery.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

56602-33-6 - Risk and Safety:

Risk Codes
R37/38 - Irritating to respiratory system and skin.
R44 - Risk of explosion if heated under confinement
R36/37/38 - Irritating to eyes, respiratory system and skin.
R11 - Highly Flammable
R2 - Risk of explosion by shock, friction, fire or other sources of ignition
Safety Description
S24/25 - Avoid contact with skin and eyes.
S37/39 - Wear suitable gloves and eye/face protection
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S35 - This material and its container must be disposed of in a safe way.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs UN 1325 4.1/PG 2
WGK Germany 3
FLUKA BRAND F CODES 8-10-21
Hazard Note Irritant
Hazard Class 4.1
Packing Group Ⅱ

Application:

BOP Reagent (CAS: 56602-33-6) is a peptide coupling reagent which suppresses racemization. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.
BOP Reagent is a phosphonium coupling reagent used for peptide synthesis. BOP can be employed in presence of a base such as triethylamine or Hünig’s base and forms HOBt in situ, which then generates an activated ester. BOP is a very effective coupling reagent, achieving high yields, low epimerisation and high conversion rates. However, it forms the extremely toxic and carcinogenic HMPA in situ, therefore the equally efficient pyrrolidino derivative PyBOP was introduced, which leads to a less toxic by-product.
BOP Reagent is used as a reagent for peptide coupling, lactonization, selective esterification, amidation of alfa amino acids without racemization and synthesis of magnolamide for antioxidative activity and catalyst for 9-acridinecaroboxamide derivative. It is also used as a precursor for the synthesis of phenyl esters of amino acids.