Candesartan Cilexetil Intermediate Eethyl Ester C6 CAS 139481-41-7 Assay >99.0% (HPLC) Factory

Short Description:

Chemical Name: Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate

Candesartan Cilexetil Intermediate Eethyl Ester C6

CAS: 139481-41-7

Assay: >99.0% (HPLC)  

Appearance: White to Off-White Powder

Intermediate of Candesartan Cilexetil

E-Mail: alvin@ruifuchem.com


Product Detail

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Description:

Chemical Properties:

Chemical Name Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate
Synonyms Candesartan Cilexetil Intermediate Eethyl Ester C6; Ethyl 1-((2'-Cyano-[1,1'-Biphenyl]-4-yl)methyl)-2-Ethoxy-1H-Benzo[d]imidazole-7-Carboxylate
CAS Number 139481-41-7
CAT Number RF-PI1886
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C26H23N3O3
Molecular Weight 425.48
Density  1.19
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Off-White Powder
Melting Point 128.0~132.0℃
Related Impurities
Individual Impurity <0.50%
Total Impurities <1.00%
Loss on Drying <1.00%
Residue on Ignition <0.50%
Proton NMR Spectrum Conforms to Structure
Infrared Spectrum Conforms to Structure
Test Standard Enterprise Standard
Usage Intermediate of Candesartan Cilexetil (CAS: 145040-37-5)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

1

FAQ:

Application:

Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate, also known as Candesartan Cilexetil Intermediate Eethyl Ester C6, (CAS: 139481-41-7) is an intermediate of Candesartan Cilexetil (CAS: 145040-37-5). Candesartan Cilexetil is a prodrug of the potent, long-acting, and selective angiotensin II type 1 receptor AT1 antagonist, candesartan. It is rapidly hydrolyzed to candesartan during gastrointestinal absorption. Candesartan Cilexetil takes effects through selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland, further blocking the vasoconstrictor and aldosterone-secreting effects of angiotensin II. Candesartan Cilexetil is mainly used for the treatment of high blood pressure (hypertension) and heart failure.

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