Gatifloxacin-Q-Acid CAS 112811-72-0 Purity >98.0% (HPLC)

Short Description:

Chemical Name: Gatifloxacin-Q-Acid

Synonyms: Difluoro Methoxy Gatifloxacin

CAS: 112811-72-0

Purity: >98.0% (HPLC)

Appearance: Off-White to Light Yellow Powder 

Intermediate of Gatifloxacin / Moxifloxacin Hydrochloride

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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112811-72-0 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Gatifloxacin-Q-Acid (CAS: 112811-72-0) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Gatifloxacin-Q-Acid, Please contact: alvin@ruifuchem.com

Gatifloxacin Related Intermediates:

112811-71-9
Gatifloxacin-Q-Acid 112811-72-0
112811-59-3
160738-57-8
180200-66-2
316819-28-0

 

112811-72-0 - Chemical Properties:

Chemical Name Gatifloxacin-Q-Acid 
Synonyms 1-Cyclopropyl-6,7-Difluoro-8-Methoxy-4-Oxo-3-Quinolinecarboxylic Acid; 1-Cyclopropyl-6,7-Difluoro-8-Methoxy-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid; 1-Cyclopropyl-6,7-Difluoro-1,4 Dihydro-8-Methoxy-4-Oxo-3-Quinoline Carboxylic Acid; Ciprofloxacin Difluoro 8-Methoxy Impurity; Moxifloxacin Difluoro Methoxy Acid Impurity; USP Gatifloxacin Related Compound C; Difluoro Methoxy Gatifloxacin
Stock Status In Stock, Commercial Production  
CAS Number 112811-72-0
Molecular Formula C14H11F2NO4
Molecular Weight 295.24 g/mol
Melting Point 192.0~194.0℃ 
Density 1.581±0.06 g/cm3 
COA & MSDS Available
Sample  Available
Origin Shanghai, China
Brand Ruifu Chemical

112811-72-0 - Specifications:

Items Specifications  Results
Appearance Off-White to Light Yellow Powder
Complies      
Loss on Drying <0.50% 0.30% 
Gatifloxacin Ester <0.50% 0.30% 
Any Other Impurity <0.30% 0.19%
Purity / Analysis Method >98.0% (HPLC)  99.15% 
Infrared Spectrum Consistent with Structure Complies 
1H NMR Spectrum Consistent with Structure Complies
LCMS Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications
Application Intermediate of Gatifloxacin / Moxifloxacin Hydrochloride 

Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

112811-72-0 - Risk and Safety:

Hazard Symbols Xn - Harmful 
Risk Codes 22 - Harmful if swallowed
Safety Description 24/25 - Avoid contact with skin and eyes.
HS Code 2933 4900.90
Hazard Class IRRITANT

112811-72-0 - Application:

Gatifloxacin-Q-Acid (CAS: 112811-72-0) is an intermediate of Gatifloxacin (CAS: 112811-59-3) / Moxifloxacin Hydrochloride (CAS: 186826-86-8).
Gatifloxacin (brand names Gatiflo, Tequin, and Zymar) is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.
It was patented in 1986 and approved for medical use in 1999. Gatifloxacin belongs to a class of drugs known as quinolone antibiotics and is used to treat acute sinus, lung, or urinary tract infections and sexually transmitted bacterial infection.This drug may be taken orally, in tablet form, or by injection.
Moxifloxacin Hydrochloride is a fluoroquinolone antibiotic developed by Bayer Pharmaceuticals (Germany.) It can be used to treat community-acquired pneumonia caused by Staphylococcus aureus, baccilus, pneumococcus, mucositis Moraxella, and Klebsiella pneumoniae, acute chronic bronchitis attacks, and acute sinusitis. For the treatment of adult bacterial lung infections, paranasal sinus, skin, and abdominal cavity. Also used to treat community-acquired pneumonia, chronic bronchitis, urogenital infection, and acute sinusitis. 

112811-72-0 - Medical Uses:

The synthesis of novel quinoline derivatives begins with the reaction of the starting material, 1-Cyclopropyl-6,7-Difluoro-8-Methoxy-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid (CAS: 112811-72-0), with a variety of reagents such as alcohols, amines and acids. These reactions produce a range of quinoline derivatives with different functionalities. The compounds produced can then be further modified to generate new compounds with potential therapeutic activities. For example, the reaction of the starting material with an amine can produce a quinolone derivative which can then be subjected to a range of other reactions such as reduction, oxidation or alkylation to produce a range of compounds with different properties. These compounds can then be tested for their potential therapeutic activities. 

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