Apixaban Intermediate CAS 1267610-26-3 1-(4-Aminophenyl)-3-Morpholino-5,6-Dihydropyridin-2(1H)-one Purity ≥99.0% (HPLC)
Ruifu Chemical is the leading manufacturer of 1-(4-Aminophenyl)-3-Morpholino-5,6-Dihydropyridin-2(1H)-one (CAS: 1267610-26-3) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase Apixaban intermediates, Please contact: alvin@ruifuchem.com
| Chemical Name | 1-(4-Aminophenyl)-3-Morpholino-5,6-Dihydropyridin-2(1H)-one |
| Synonyms | 1-(4-Aminophenyl)-5,6-Dihydro-3-(4-Morpholinyl)-2(1H)-Pyridinone; Apixaba Inretmediate A; Apixaban int. A; Apixaban Impurity S; Apixaban Impurity 47; Apixaban Related Impurities 2 |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 1267610-26-3 |
| Molecular Formula | C15H19N3O2 |
| Molecular Weight | 273.33 g/mol |
| Melting Point | >246℃ |
| Density | 1.277±0.06 g/cm3 |
| COA & MSDS | Available |
| Origin | Shanghai, China |
| Category | Intermediate of Apixaban (CAS: 503612-47-3) |
| Brand | Ruifu Chemical |
| Items | Inspection Standards | Results |
| Appearance | Off-White to Light Yellow Powder | Off-White Powder |
| Purity / Analysis Method | ≥99.0% (HPLC) | 99.65% |
| Max. Individual Impurity | ≤0.20% | 0.12% |
| Loss on Drying | ≤0.50% | 0.3% |
| Infrared Spectrum | Conforms to Structure | Complies |
| NMR Spectrum | Conforms to Structure | Complies |
| Conclusion | The product has been tested & complies with the given specifications | |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
1-(4-Aminophenyl)-3-Morpholino-5,6-Dihydropyridin-2(1H)-one (CAS: 1267610-26-3) is an intermediate in the synthesis of Apixaban (CAS: 503612-47-3), A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. Apixaban is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. Eliquis (Apixaban), a direct inhibitor of factor Xa (FXa), was approved by the European Commission on May 18, 2011 for prevention of venous thromboembolic events (VTE) in adult patients who have undergone elective hip or knee replacement surgery.
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