L-Glutamic Acid α-Benzyl Ester CAS 13030-09-6 (H-Glu-OBzl) Assay >98.5% (HPLC) High Quality

Short Description:

Chemical Name: L-Glutamic Acid α-Benzyl Ester 

Synonyms: H-Glu-OBzl; 1-Benzyl L-Glutamate 

CAS: 13030-09-6 

Assay: >98.5% (HPLC) 

Appearance: White or Off-White Crystalline Powder  

Amino Acids & Derivatives, High Quality 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of L-Glutamic Acid α-Benzyl Ester (H-Glu-OBzl) (CAS: 13030-09-6) with high quality. Ruifu Chemical supplys a series of amino acids and derivatives. We can provide worldwide delivery, small and bulk quantities available. If you need L-Glutamic Acid α-Benzyl Ester, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name L-Glutamic Acid α-Benzyl Ester  
Synonyms H-Glu-OBzl; H-L-Glu-OBzl; L-Glutamic Acid 1-Benzyl Ester; 1-Benzyl L-Glutamate; L-Glutamic Acid alpha-Benzyl Ester; (S)-4-Amino-5-(Benzyloxy)-5-Oxopentanoic Acid
Stock Status In Stock 
CAS Number 13030-09-6 
Molecular Formula C12H15NO4
Molecular Weight 237.26  
Melting Point 140.0~150.0℃ 
Density 1.245±0.06 g/cm3 
Sensitive Air Sensitive, Moisture Sensitive, Heat Sensitive
Storage Temp.  Sealed in Dry, Store at Room Temperature
COA & MSDS Available
Classification Amino Acids & Derivatives 
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance White or Off-White Crystalline Powder   Conforms          
Loss on Drying <0.50% 0.24%
Melting Point 140.0~150.0℃ 146.0~150.0℃
Assay / Analysis Method  >98.5% (HPLC)   98.84%
Specific Rotation [α]20/D +10.0 to +12.0° (C=1, 1mol/L HCl) Conforms
Infrared Spectrum  Conforms to Structure Conforms
Proton NMR Spectrum  Conforms to Structure Conforms
Conclusion This Product by Inspection Accords with the Enterprise Standard
Main Uses Amino Acids and Derivatives; Pharmaceutical Intermediates

Process of Production:

1. L-Glutamic Acid, Sodium Hydroxide, Water, Acetone, Boc-Anhydride
2. Boc-L-Glu-OH reacted with Benzyl Bromide and Triethylamine to obtain Boc-Glu-OBzl
3. HCL/EA Take off Boc-, Adjust the PH, Obtain H-Glu-OBzl
4. Solvents Used: DMF, Ethyl Acetate, Ethanol 

Method of Analysis:

1. Purity (HPLC)
1.1 Instruments
High performance liquid chromatography, UV3000 detector.
Electronic analytical balance
1.2 Reagents
Acetonitrile (chromatographic grade), TFA (chromatographic grade)
1.3 Chromatographic conditions
1.3.1 Column: C18 column, 5 μl * 250 * 4.6 mm
1.3.2 Detection wavelength: 220nm
Flow rate: 1.0 mL/min
Injection volume:10 μL(for reference)
Diluent: acetonitrile
Run time: 20 minutes
1.4 Mobile phase preparation
Mobile phase A (0.1% Trifluoroacetic acid Water): accurately absorb 1.0 ml TFA diluted to 1000 ml with water, mix and degas.
Mobile phase B (0.1% Trifluoroacetic acid Acetonitrile): accurately absorb 1.0 ml TFA, diluted to 1000 ml with acetonitrile, mix and degas.
1.5 Gradient Program
Time (min) A% B%
0:00 90 10
10.00 10 90
15.00 10 90
15.01 90 10
20.00 90 10
1.6 Preparation of sample solution
Weigh 0.1 g sample and dissolve it with acetonitrile and dilute it to 100ml. Shake well for future use, or the same concentration. Prepare two samples in parallel.
1.7 Sample Determination
Analyze the sample according to the following sampling procedure:
1) More than 1 injection of blank solution
2) 1 injection of sample solution 1#
3) 1 injection of sample solution 2#
1.8.0 Calculations
1.8.1 The peak area normalization method was used to calculate the purity of HPLC.
1.8.2 The relative mean deviation of the purity of two needles shall not be greater than 1%
1.8.3 If the results of both injections meet the acceptance criteria, take the average purity as the final result.

Structures of Impurities:

                                                          

                         

Package & Storage:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool, dry and ventilated warehouse away from incompatible substances. Protect from light and moisture.

Package & Storage:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool, dry and ventilated warehouse away from incompatible substances. Protect from light and moisture.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

L-Glutamic Acid α-Benzyl Ester (H-Glu-OBzl) (CAS: 13030-09-6), Amino Acids and Derivatives; Pharmaceutical Intermediates.

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