5-(2R)-2-Oxiranyl-8-Benzyloxy-2(1H)-Quinolinone CAS 173140-90-4 Indacaterol Maleate Intermediate Purity >98.0% (HPLC)
Commercial Supply Indacaterol Maleate (CAS: 753498-25-8) Related Intermediates:
5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride CAS: 312753-53-0
8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline CAS: 100331-89-3
5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone CAS: 173140-90-4
| Chemical Name | 5-(2R)-2-Oxiranyl-8-Benzyloxy-2(1H)-Quinolinone |
| Synonyms | 8-Benzoxy-5-(R)-Oxiranyl-1H-Quinolin-2-One |
| CAS Number | 173140-90-4 |
| CAT Number | RF-PI127 |
| Stock Status | In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula | C18H15NO3 |
| Molecular Weight | 293.31 |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | Pale Yellow to Off-White Powder |
| Purity / Analysis Method | ≥98.0% (HPLC) |
| Moisture (K.F) | ≤1.0% |
| Specific Rotation | -20.0° ~ -26.0° (C=1 DMF) |
| Test Standard | Enterprise Standard |
| Usage | Indacaterol Maleate (CAS: 753498-25-8) Intermediate |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone (CAS: 173140-90-4) with high quality. It is an intermediate typically in the synthesis of Indacaterol Maleate (CAS: 753498-25-8).
Indacaterol Maleate (CAS: 753498-25-8) is a new, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist and bronchodilator. It is used in the treatment of chronic obstructive pulmonary disease (COPD) and asthma. The European Medicines Agency (EMA) approved indacaterol as a drug in 2009 under the Onbrez trade name while in the United States the Food and Drug Administration approved it under the trade name Arcapta in 2011. The drug is manufactured as its maleate salt form. Also, indacaterol is a chiral molecule; however, only the pure R-enantiomer is distributed. It needs to be taken only once a day, unlike competitors formoterol and salmeterol.
