4-(Carboxybutyl)triphenylphosphonium Bromide CAS 17814-85-6 Purity >98.0% (HPLC)

Short Description:

4-(Carboxybutyl)triphenylphosphonium Bromide

CAS: 17814-85-6

Purity: >98.0% (HPLC)

Appearance: White to Off-White Powder

Contact: Dr. Alvin Huang

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E-Mail: alvin@ruifuchem.com

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Product Detail

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Description:

Ruifu Chemical is the leading manufacturer of 4-(Carboxybutyl)triphenylphosphonium Bromide (CAS: 17814-85-6) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase 4-(Carboxybutyl)triphenylphosphonium Bromide, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name	4-(Carboxybutyl)triphenylphosphonium Bromide
Synonyms	5-(Triphenylphosphonio)pentanoic Acid Bromide; Carboxybutyltriphenylphosphonium Bromide; Triphenyl(4-carboxybutyl)phosphonium Bromide
Stock Status	In Stock, Commercial Production
CAS Number	17814-85-6
Molecular Formula	C23H24BrO2P
Molecular Weight	443.32 g/mol
Melting Point	205.0 to 209.0℃
Flash Point	195℃(383°F)
Density	1.371 at 20℃
Sensitive	Hygroscopic
Solubility	Soluble in Ethanol, Methanol, Water. Insoluble in Toluene and Hexane
Solubility in Methanol	Almost Transparency
COA & MSDS	Available
Sample	Available
Origin	Shanghai, China
Brand	Ruifu Chemical

Specifications:

Items	Inspection Standards	Results
Appearance	White to Off-White Powder	Complies
Purity / Analysis Method	>98.0% (HPLC)	99.36%
Triphenylphosphine	<0.50%	0.45%
Triphenylphosphine Oxide	<0.50%	0.13%
Melting Point	205.0 to 209.0℃	206.0~207.0℃
Water by Karl Fischer	<0.50%	0.3%
Infrared Spectrum	Consistent with Structure	Complies
Conclusion	The product has been tested and complies with the given specifications

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Hygroscopic. Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture. Keep away from oxidizing agents.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

17814-85-6 - Safety Information:

Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
UN IDs 3278
WGK Germany 3
HS Code 2931900090

17814-85-6 - Background:

Prostaglandin drugs are a large class of drugs developed by chemical modification on the basis of functional substances found in human prostaglandins. They belong to biomimetic synthetic compounds and are widely used in the treatment of cardiovascular, gynecological, digestive system, ophthalmology and other diseases. The side chain 4-(Carboxybutyl)triphenylphosphonium Bromide (CAS: 17814-85-6) is required in all known prost drug synthesis. The acquisition of this side chain is essential for the synthesis of prost drugs.

17814-85-6 - Application:

4-(Carboxybutyl)triphenylphosphonium Bromide (CAS: 17814-85-6) is an organic synthesis intermediate and pharmaceutical intermediate, which can be used in laboratory organic synthesis and pharmaceutical research and development In the process, it is mainly used as an intermediate of the bulk drug Bimatoprost.

17814-85-6 - Synthesis Method:

5-Bromo-1-Pentanol is reacted with hypochlorite in a solvent, TEMPO and a phase transfer catalyst, and then 5-Bromovaleric Acid is collected from the reaction product. 5-Bromovaleric Acid is reacted with triphenylphosphine in a solvent, and then from the reaction liquid, the target product 4-(Carboxybutyl)triphenylphosphonium Bromide was collected.

17814-85-6 - Uses:

4-(Carboxybutyl)triphenylphosphonium Bromide (CAS: 17814-85-6) is a compound useful in organic synthesis.
Used as a platform for delivery of pro-apoptotic peptides into the mitochondria of tumor cells
Reactant for preparation of:
Ring skeletons via ring closing metathesis and double bond migration ring closing metathesis reactions
Methyl alkenyl quinolones as antimycobacterial agents
Prostaglandins and their drug analogs via Gold-catalyzed Meyer-Schuster rearrangement
Diphenylmethylpiperazines as N-type calcium channel blockers as potential therapeutic agents
Folate receptor-specific glycinamide ribonucleotide formyltransferase (GARFTase) inhibitors with antitumor activity
Cycloalkylidene alkanols with antileishmanial activity, via Wittig reaction