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4-Aminopyrazolo[3,4-d]pyrimidine CAS 2380-63-4 Ibrutinib Intermediate Purity >98.0% (HPLC) Featured Image
  • 4-Aminopyrazolo[3,4-d]pyrimidine CAS 2380-63-4 Ibrutinib Intermediate Purity >98.0% (HPLC)

4-Aminopyrazolo[3,4-d]pyrimidine CAS 2380-63-4 Ibrutinib Intermediate Purity >98.0% (HPLC)

Short Description:

Chemical Name: 4-Aminopyrazolo[3,4-d]pyrimidine 

CAS: 2380-63-4

Purity: >98.0% (HPLC) (T) 

Appearance: Off-White to Light Brown Powder 

Intermediate of Ibrutinib (CAS: 936563-96-1)

Contact: Dr. Alvin Huang   

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 4-Aminopyrazolo[3,4-d]pyrimidine (CAS: 2380-63-4) with high quality. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in this product, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com

Intermediates of Ibrutinib:

Ibrutinib CAS 936563-96-1                           
3-Hydroxypiperidine CAS 6859-99-0 
1-Boc-3-Hydroxypiperidine CAS 85275-45-2
(S)-1-Boc-3-Hydroxypiperidine CAS 143900-44-1
4-Phenoxybenzoic Acid  CAS 2215-77-2
4-Phenoxyphenylboronic Acid CAS 51067-38-0
4-Aminopyrazolo[3,4-d]pyrimidine CAS 2380-63-4
4-Amino-3-Iodo-1H-Pyrazolo[3,4-d]pyrimidine  CAS 151266-23-8 
Ibrutinib Deacryloylpiperidine CAS 330786-24-8 
5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile CAS 330792-70-6

Chemical Properties:

Chemical Name 4-Aminopyrazolo[3,4-d]pyrimidine  
Synonyms 1H-Pyrazolo[3,4-d]pyrimidin-4-Amine; 4-Amino-4H-Pyrazolo[3,4-d]pyrimidine; 4H-Pyrazolo[3,4-d]pyrimidin-4-Amine; 4-Amino-1H-Pyrazolo[3,4-d]pyrimidine 
CAS Number 2380-63-4 
Related CAS 20289-44-5
Stock Status In Stock, Production Scale Up to Tons
Molecular Formula C5H5N5 
Molecular Weight 135.13  
Melting Point >325℃(lit.)
Solubility in Water Insoluble in Water
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance Off-White to Light Brown Powder
Purity / Analysis Method >98.0% (HPLC) 
Purity / Analysis Method >98.0% (Nonaqueous Titration) 
Loss on Drying <0.50%
Water Content (K.F) <0.50%
Total Impurities <2.00%
1 H NMR Spectrum Consistent With Structure
Test Standard Enterprise Standard
Usage Pharmaceutical Intermediates

Package & Storage:

Package: Bottle, Aluminum foil bag, 25kg/Cardboard Drum, or according to customer's requirement

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.

Advantages? Excellent quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

2380-63-4 - Risk and Safety:

Hazard Symbols T - Toxic
Risk Codes R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S22 - Do not breathe dust.
S36 - Wear suitable protective clothing.
UN IDs UN 2811 6.1/PG 3
WGK Germany 3
RTECS UR0717000
TSCA Yes
Hazard Class 6.1
Packing Group III
Toxicity LD50 oral in rat: 141mg/kg

2380-63-4 - Application:

4-Aminopyrazolo[3,4-d]pyrimidine (CAS: 2380-63-4) is used as a pharmaceutical intermediate, it can be used as an intermediate of Ibrutinib (CAS: 936563-96-1). Ibrutinib is a kind of Bruton tyrosine kinase (BTK) inhibitor, it could be used for the treatment of chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL).  

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