1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine CAS 253168-94-4 Purity >98.0% (HPLC) Apremilast Intermediate

Short Description:

1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine

CAS: 253168-94-4

Purity: >98.0% (HPLC)

Appearance: White to Off-White Solid

Intermediate of Apremilast (CAS: 608141-41-9)

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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253168-94-4 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine (CAS: 253168-94-4) with high quality, intermediate of Apremilast (CAS: 608141-41-9). Apremilast is used for the treatment of active psoriatic arthritis (PsA) and moderate to severe chronic plaque psoriasis (PSOR). Ruifu Chemical can provide high-quality Apremilast intermediates and impurities.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Apremilast intermediates and impurities or other products, please e-mail: alvin@ruifuchem.com

Intermediates of Apremilast:

Apremilast	CAS 608141-41-9
3-Acetamidophthalic Anhydride	CAS 6296-53-3
3-Ethoxy-4-Methoxybenzonitrile	CAS 60758-86-3
3-Ethoxy-4-Methoxybenzaldehyde	CAS 1131-52-8
1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine	CAS 253168-94-4
(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine	CAS 608141-42-0
(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylamine N-Acetyl-L-LeucineSalt	CAS 608141-43-1

253168-94-4 - Chemical Properties:

Chemical Name	1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine
Synonyms	3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzenemethanamine; 1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine; 1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine; 2-(3-Ethoxy-4-methoxyphenyl)-1-(methylsulfonyl)eth-2-ylamine; Apremilast EP Impurity H
Stock Status	In Stock, Commercial Production
CAS Number	253168-94-4
Molecular Formula	C12H19NO4S
Molecular Weight	273.35 g/mol
Melting Point	119.0 to 123.0℃
Density	1.195±0.06 g/cm3
Solubility	Soluble in Methanol (Almost Transparency)
Storage Temperature	Store Long-Term in a Cool and Dry Place
COA & MSDS	Available
Origin of Product	Shanghai, China
Product Categories	Apremilast Intermediate
Brand	Ruifu Chemical

253168-94-4 - Specifications:

Items	Specifications	Results
Appearance	White to Off-White Solid	White Solid
Melting Point	119.0~123.0℃	120.2℃
Loss on Drying	<1.00%	0.23%
Purity / Analysis Method	>98.0% (HPLC)	98.35%
1H NMR Spectrum	Conforms to Structure	Conforms
Conclusion	The product has been tested and complies with the given specifications
Application	Intermediate of Apremilast (CAS: 608141-41-9)

253168-94-4 - Package/Storage/Shipping:

Package: Fluorinated bottle, Aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.

253168-94-4 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

253168-94-4 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

253168-94-4 - Safety Information:

HS Code

2934999099

253168-94-4 - Application:

1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine (CAS: 253168-94-4), intermediate of Apremilast (CAS: 608141-41-9). Apremilast is the first and only oral phosphodiesterase IV (PDE- 4) inhibitor and anti-tumor necrosis factor alpha (TNFa) agent launched in the USA by Celgene for the treatment of active psoriatic arthritis (PsA). Apremilast was also approved for the treatment of moderate to severe plaque psoriasis (PSOR) in the USA. Later, this drug was also approved in the European Union (EU) for both indications.