N-(4-Cyanophenyl)glycine CAS 42288-26-6 Dabigatran Etexilate Mesylate Intermediate Purity >99.0% (HPLC)
Shanghai Ruifu Chemical is the leading manufacturer of N-(4-Cyanophenyl)glycine (CAS: 42288-26-6) with high quality, intermediate of Dabigatran Etexilate Mesylate (CAS: 872728-81-9). Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase N-(4-Cyanophenyl)glycine, Please contact: alvin@ruifuchem.com
| Chemical Name | N-(4-Cyanophenyl)glycine |
| Synonyms | Dabigatran Etexilate Intermediate 2; N-(p-Cyanophenyl)glycine; N-(4-Cyano-Phenyl)-Glycine; 2-[(4-Cyanophenyl)amino]acetic Acid; 2-(4-Cyanophenylamino)acetic Acid; Dabigatran Cyanopheny Impurity |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 42288-26-6 |
| Molecular Formula | C9H8N2O2 |
| Molecular Weight | 176.18 g/mol |
| Melting Point | 227.0~230.0℃ |
| Density | 1.30±0.10 g/cm3 |
| COA & MSDS | Available |
| Free Sample | Available |
| Origin | Shanghai, China |
| Category | Intermediate of Dabigatran Etexilate Mesylate (CAS: 872728-81-9) |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | White to Off-White Powder | Off-White Powder |
| Melting Point | 227.0~230.0℃ | 227.0~228.0℃ |
| Loss on Drying | <0.50% | 0.09% |
| Residue on Ignition | <0.50% | 0.26% |
| Assay / Analysis Method | 98.0%~102.0% | 100.6% |
| Purity / Analysis Method | >99.0% (HPLC) | 99.5% |
| 4-Aminobenzonitrile | <1.00% | Complies |
| Other Single Impurity | <0.25% | <0.25% |
| Total Impurities | <1.00% | 0.50% |
| Heavy Metals | <10ppm | <10ppm |
| 1H NMR Spectrum | Consistent with Structure | Complies |
| Conclusion | The product has been tested and complies with the given specifications | |
| Application | Intermediate of Dabigatran Etexilate Mesylate (CAS: 872728-81-9) | |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
| Mobile Phase | Buffer Solution (0.025mol/L KH2PO4, pH=3.1):Acetonitrile=60:40 |
| Column | Kromasil 100-5 C18 250*4.6mm*5μm |
| Dilute | Water:Acetonitrile=50:50 |
| Flow | 1.0mL/min |
| Column Temperature | 25℃ |
| Run Time | 30min |
| Wavelength | 254nm |
| Injection Volume | 10μL |
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
N-(4-Cyanophenyl)glycine (CAS: 42288-26-6), intermediate of Dabigatran Etexilate Mesylate (CAS: 872728-81-9). Dabigatran Etexilate is a new synthetic direct thrombin inhibitor. It is a precursor of dabigatran and a non peptide thrombin inhibitor. After oral administration, Dabigatran etexilate was transformed into dabigatran with direct anticoagulant activity in vivo. Dabigatran binds to the fibrin specific binding site of thrombin and prevents fibrinogen from cleaving to fibrin, thus blocking the final step of coagulation cascade network and thrombosis. Dabigatran can dissociate from fibrin thrombin conjugates and play a reversible anticoagulant effect.
