Tofacitinib Citrate Intermediate CAS 477600-71-8 Purity >97.0% (HPLC) e.e. >97.0%
Ruifu Chemical is the leading manufacturer of (2R,3R)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid compd. with (3R,4R)-N,4-dimethyl-1-(phenylmethyl)-3-piperidinamine (CAS: 477600-71-8) with high quality, intermediate of Tofacitinib Citrate (CAS: 540737-29-9). Ruifu Chemical has been supplying pharmaceutical intermediates and APIs, fine chemicals more than 15 years. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service. Purchase Tofacitinib Citrate Intermediates, please contact us by e-mail: alvin@ruifuchem.com
Chemical Name | (2R,3R)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid compd. with (3R,4R)-N,4-dimethyl-1-(phenylmethyl)-3-piperidinamine |
Synonyms | (2R,3R)-2,3-Bis[(4-methylbenzoyl)oxy]butandioic acid / (3R,4R)-N,4-dimethyl-1-(phenylmethyl)-3-piperidinamine; (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine ((2R,3R)-2,3-bis((4-methylbenzoyl)oxy)succinate) (2:1); (2R,3R)-2,3-bis(4-methylbenzoyloxy)butanedioic acid / bis((3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine); 3-bis(4-Methylbenzoyloxy)succinate) |
Stock Status | In Stock |
CAS Number | 477600-71-8 |
Molecular Formula | C48H62N4O8 |
Molecular Weight | 823.03 g/mol |
Melting Point | 224.0-227.0℃ |
Storage Temperature | Store Long-Term at 2-8℃ |
COA & MSDS | Available |
Origin of Product | Shanghai, China |
Product Categories |
Pharmaceutical Intermediates |
Brand | Ruifu Chemical |
Items | Specifications | Results |
Appearance | White to Off-White Solid | White Solid |
Melting Point | 224.0-227.0℃ | 224.5-226.0℃ |
Water by Karl Fischer | <1.00% | 0.81% |
Purity / Analysis Method | >97.0% (HPLC) | 99.5% |
Chiral Purity (e.e.%) | >97.0% (HPLC) | 99.5% |
Infrared Spectrum | Conforms to Structure | Conforms |
1H NMR Spectrum | Conforms to Structure | Conforms |
Conclusion | The product has been tested and complies with the given specifications | |
Application | Intermediate of Tofacitinib Citrate (CAS: 540737-29-9) |
Package: Fluorinated bottle, Aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃), well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
HS Code | 2942000000 |
(2R,3R)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid compd. with (3R,4R)-N,4-dimethyl-1-(phenylmethyl)-3-piperidinamine (CAS: 477600-71-8), intermediate of Tofacitinib Citrate (CAS: 540737-29-9). Tofacitinib Citrate is a king of drugs developed by the US pharmaceutical company Pfizer for treating rheumatoid arthritis, trade name Xeljanz, for the treatment of methotrexate inadequate response or intolerance to severe active rheumatoid arthritis (RA) in adult patients. This product is a Janus kinase inhibitor, administered twice daily.
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