5-Amino-3-(Trifluoromethyl)picolinonitrile CAS 573762-62-6 Apalutamide Intermediate Purity >98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 5-Amino-3-(Trifluoromethyl)picolinonitrile (CAS: 573762-62-6) with high quality, intermediate of Apalutamide (CAS: 956104-40-8). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Apalutamide Intermediates, Please contact: alvin@ruifuchem.com
| Chemical Name | 5-Amino-3-(Trifluoromethyl)picolinonitrile |
| Synonyms | 5-Amino-3-(Trifluoromethyl)pyridine-2-Carbonitrile; 5-Amino-3-(Trifluoromethyl)2-Cyanopyridine; 5-Amino-2-Cyano-3-(Trifluoromethyl)pyridine; Apalutamide Impurity 10 |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 573762-62-6 |
| Molecular Formula | C7H4F3N3 |
| Molecular Weight | 187.12 g/mol |
| Density | 1.45±0.10 g/cm3 |
| COA & MSDS | Available |
| Origin | Shanghai, China |
| Hazard Class | 6.1 |
| Packing Group | Ⅲ |
| Category | Intermediate of Apalutamide (CAS: 956104-40-8) |
| Brand | Ruifu Chemical |
| Items | Inspection Standards | Results |
| Appearance | Light Yellow to Yellow Solid | Complies |
| Water by Karl Fischer | <0.50% | 0.35% |
| Purity / Analysis Method | >98.0% (HPLC) | 99.03% |
| Infrared Spectrum | Consistent with Structure | Complies |
| 1H NMR Spectrum | Consistent with Structure | Complies |
| Conclusion | The product has been tested and complies with the given specifications | |
| Application | Intermediate of Apalutamide (CAS: 956104-40-8) | |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
5-Amino-3-(Trifluoromethyl)picolinonitrile (CAS: 573762-62-6), is a pyridine heterocyclic organic compound, which can be used as pharmaceutical intermediates. 5-Amino-3-(Trifluoromethyl)picolinonitrile is an intermediate of Apalutamide (CAS: 956104-40-8). Apalutamide is a second-generation antiandrogen used in the treatment of prostate cancer. It is a potent antagonist of androgen receptor with IC50 value of 16 nM. Binds androgen receptors, thereby inhibiting nuclear translocation, DNA binding and transcriptional activation. Apalutamide has therapeutic applications in non-metastatic, castration-resistant prostate cancer.
Apalutamide is used to treat certain types of castration-resistant prostate cancer or prostate cancer that has not spread to other parts of the body, but has not been helped by other medical treatments. Apalutamide is in a class of medications called androgen receptor inhibitors. It works by blocking the effects of androgen to stop the growth and spread of cancer cells. On September 17, 2019, the Food and Drug Administration approved Apalutamide (ERLEADA, Janssen Biotech, Inc) for patients with metastatic castration-sensitive prostate cancer (mCSPC). Apalutamide was initially approved in 2018 for patients with non-metastatic castration-resistant prostate cancer.
