4,4,4-Trifluoro-1-(p-Tolyl)-1,3-Butanedione CAS 720-94-5 Celecoxib Intermediate Purity >99.0% (GC)
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of 4,4,4-Trifluoro-1-(p-Tolyl)-1,3-Butanedione (CAS: 720-94-5) with high quality, an important intermediate of Celecoxib (CAS: 169590-42-5). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Celecoxib Intermediates, Please contact: alvin@ruifuchem.com
| Chemical Name | 4,4,4-Trifluoro-1-(p-Tolyl)-1,3-Butanedione |
| Synonyms | 4,4,4-Trifluoro-1-(4-Methylphenyl)-1,3-Butanedione; 4,4,4-Trifluoro-1-(p-Tolyl)butane-1,3-Dione; 4,4,4-Trifluoro-1-(4-Methylphenyl)butane-1,3-Dione; 1-(4-Methylphenyl)-4,4,4-Trifluorobutane-1,3-Dione |
| Impurity | Celecoxib Related Compound 4; Celecoxib - Impurity G |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 720-94-5 |
| Molecular Formula | C11H9F3O2 |
| Molecular Weight | 230.19 g/mol |
| Melting Point | 45.0 to 49.0℃ |
| Density | 1.252±0.06 g/cm3 |
| Sensitive | Heat Sensitive |
| Solubility | Soluble in Methanol |
| COA & MSDS | Available |
| Sample | Available |
| Origin | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Inspection Standards | Results |
| Appearance | Light Yellow to Yellow Powder |
Yellow Powder |
| Melting Point | 45.0~49.0℃ | Complies |
| Water by Karl Fischer | <0.50% | 0.2% |
| Purity / Analysis Method | >99.0% (GC) | 99.8% |
| Infrared Spectrum | Consistent with Structure | Complies |
| 1H NMR Spectrum | Consistent with Structure | Complies |
| Conclusion | The product has been tested and complies with the given specifications | |
| Application | Intermediate of Celecoxib (CAS: 169590-42-5) | |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Class IRRITANT
4,4,4-Trifluoro-1-(p-Tolyl)-1,3-Butanedione (CAS: 720-94-5) is an intermediate of Celecoxib (CAS: 169590-42-5). Celecoxib and Rofecoxib are two currently used COX-2 inhibitors. Successfully developed by GD Searle & Pfizer Co. (U.S.,) released in 1999, trade name: Celebrex. Celecoxib is a nonsteroidal, anti-inflammatory agent with significant analgesic and anti-inflammatory effects, causing the lowest incidence of upper gastrointestinal tract ulcers and other complications. Used clinically to treat acute and chronic osteoarthritis and rheumatoid arthritis, with an anti-inflammatory analgesic role, relieving the signs and symptoms of osteoarthritis and rheumatoid arthritis. Celecoxib is a nonsteroidal antiinflammatory drug (NSAID) first launched as Celebrex in the US for the treatment of symptoms in patients with rheumatoid arthritis (RA) and osteoarthritis (OA).
