4-(3-Chloropropyl)morpholine CAS 7357-67-7 Gefitinib Intermediate Purity >98.0% (GC)

Short Description:

Chemical Name: 4-(3-Chloropropyl)morpholine 

CAS: 7357-67-7

Purity: >98.0% (GC)

Appearance: Colorless to Light Yellow Clear Liquid

Intermediate of Gefitinib (CAS: 184475-35-2) 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Ruifu Chemical is the leading manufacturer of 4-(3-Chloropropyl)morpholine (CAS: 7357-67-7) with high quality, intermediate of Gefitinib (CAS: 184475-35-2). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase 4-(3-Chloropropyl)morpholine, Please contact: alvin@ruifuchem.com

Gefitinib Intermediates:

Chemical Properties:

Chemical Name 4-(3-Chloropropyl)morpholine 
Synonyms N-(3-Chloropropyl)morpholine; 3-Morpholinopropyl Chloride; 1-Chloro-3-(Morpholin-4-yl)propane; 1-Chloro-3-Morpholinopropane; 3-(Morpholin-4-yl)propyl Chloride; 3-Chloro-1-(Morpholin-4-yl)propane; Gefitinib Impurity VI
Stock Status In Stock, Commercial Production  
CAS Number 7357-67-7
Molecular Formula C7H14ClNO
Molecular Weight 163.65 g/mol
Boiling Point 115℃/25mmHg(lit.)   
Flash Point 91℃
Sensitive Air Sensitive, Heat Sensitive 
COA & MSDS Available
Sample  Available
Origin Shanghai, China
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance Colorless to Light Yellow Clear Liquid Complies                    
Purity / Analysis Method >98.0% (GC)  99.35%
Water by Karl Fischer  <0.50% 0.26%
Maximurn Single Impurity       <0.50% <0.50% 
Total Impurities <2.00% 0.65% 
Refractive Index n20/D 1.4705~1.4765 Complies
Density (20℃)  1.077~1.081 Complies
1 H NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications
Application Intermediate of Gefitinib (CAS: 184475-35-2)

Package/Storage/Shipping:

Package: Fluorinated Bottle, 25kg/Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory AuditFactory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
TransportationBy Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom SynthesisCan provide custom synthesis services to best fit your research needs.
Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

7357-67-7 - Safety Information:

Risk Codes
36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
RTECS QE0488000
Hazard Class IRRITANT

7357-67-7 - Application:

4-(3-Chloropropyl)morpholine (CAS: 7357-67-7) is an intermediate of Gefitinib (CAS: 184475-35-2). Gefitinib, is a drug used for certain breast, lung , and other cancers, also known as Iressa, a selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, for the treatment of prior locally advanced or metastatic non-chemical treatment or unsuitable for chemotherapysmall cell lung cancer (NSCLC). Gefitinib is a highly specific anti-tumor targeted therapy drug developed by AstraZeneca in the United Kingdom. It is the first molecularly targeted drug for the treatment of non-small cell lung cancer.

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