6-Fluoro-3-(4-Piperidinyl)-1,2-Benzisoxazole Hydrochloride CAS 84163-13-3 Risperidone Paliperidone Intermediate Purity >99.0% (HPLC)

Short Description:

6-Fluoro-3-(4-Piperidinyl)-1,2-Benzisoxazole Hydrochloride

CAS: 84163-13-3

Purity: >99.0% (HPLC)

Appearance: White to Off-White Powder 

Intermediate of Risperidone / Paliperidone 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Product Detail

Related Products

Product Tags

84163-13-3 - Description:

Ruifu Chemical is the leading manufacturer of 6-Fluoro-3-(4-Piperidinyl)-1,2-Benzisoxazole Hydrochloride (CAS: 84163-13-3) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Paliperidone Intermediates, Please contact: alvin@ruifuchem.com

84163-13-3 - Chemical Properties:

Chemical Name 6-Fluoro-3-(4-Piperidinyl)-1,2-Benzisoxazole Hydrochloride 
Synonyms 6-Fluoro-3-(Piperidin-4-yl)benzoisoxazole Hydrochloride; Paliperidone Int 2; Paliperidone Related Compound B; 4-(6-Fluoro-1,2-Benzisoxazol-3-yl)piperidine Hydrochloride
Stock Status In Stock, Commercial Production  
CAS Number 84163-13-3
Alternate CAS 84163-77-9 (Free Base)
Molecular Formula C12H13FN2O·HCl
Molecular Weight 256.71 g/mol
Melting Point 293.0~295.0℃ 
Density 1.42g/cm3 at 20℃ 
COA & MSDS Available
Sample  Available
Origin Shanghai, China
Brand Ruifu Chemical

84163-13-3 - Specifications:

Items Specifications  Results
Appearance White to Off-White Powder  White Powder   
Loss on Drying <0.50% 0.11% 
Maximum Single Impurity <0.50% <0.50%
Total Impurities  <1.00% <1.00%
Purity / Analysis Method >99.0% (HPLC)  99.2% 
1H NMR Spectrum Consistent with Structure Complies
LCMS Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications
Application Intermediate of Paliperidone (CAS: 144598-75-4)

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

84163-13-3 - Safety & Regulations:

Hazard Statements
H315: Causes skin irritation.
H319: Causes serious eye irritation.
Precautionary Statements
P264: Wash skin thoroughly after handling.
P280: Wear protective gloves/ eye protection/ face protection.
P337 + P313: If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P362: Take off contaminated clothing and wash before reuse.
HS Number 2934.99.4400

84163-13-3 - Application:

6-Fluoro-3-(4-Piperidinyl)-1,2-Benzisoxazole Hydrochloride (CAS: 84163-13-3) is used as an intermediate of Paliperidone (CAS: 144598-75-4).
Paliperidone is a dopamine and 5-HT2A antagonist that belongs to the class of atypical antipsychotics. Paliperidone is marketed by Janssen Pharmaceuticals as a controlled-release oral dosage form, which is taken once a day. The trade name is Invega, which is a drug using an osmotic pump-type controlled release system.
Paliperidone (Invega) is an atypical antipsychotic. Chemically, paliperidone is the primary active metabolite of the older atypical antipsychotic risperidone. It is indicated for the acute and maintenance treatment of schizophrenia.

  • Write your message here and send it to us