Dabigatran Etexilate Mesylate CAS 872728-81-9 Purity >99.0% (HPLC) Antithrombotic

Short Description:

Chemical Name: Dabigatran Etexilate Mesylate

Synonyms: Pradaxa Mesylate; BIBR 1048MS

CAS: 872728-81-9

Purity: >99.0% (HPLC)

Appearance: White to Light Yellow Powder 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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872728-81-9 - Description:

Ruifu Chemical is the leading manufacturer of Dabigatran Etexilate Mesylate (Pradaxa Mesylate; BIBR 1048MS) (CAS: 872728-81-9) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase Dabigatran Etexilate Mesylate, Please contact: alvin@ruifuchem.com

Intermediates of Dabigatran Etexilate Mesylate:

872728-81-9 - Chemical Properties:

Chemical Name Dabigatran Etexilate Mesylate 
Synonyms Pradaxa Mesylate; Dabigatran Etexilate Methanesulfonate; BIBR 1048MS; N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-Methyl-1H-Benzimidazol-5-yl]carbonyl]-N-2-Pyridinyl-β-Alanine Ethyl Ester Methanesulfonate
Stock Status In Stock, Commercial Production  
CAS Number 872728-81-9
Related CAS 211915-06-9 Free Base
Molecular Formula C35H45N7O8S
Molecular Weight 723.85 g/mol
Melting Point >125℃ 
COA & MSDS Available
Origin Shanghai, China
Brand Ruifu Chemical

872728-81-9 - Specifications:

Items Specifications  Results
Appearance White to Light Yellow Powder Complies      
Purity / Analysis Method >99.0% (HPLC)  99.9% 
Single Impurity <0.10% <0.10%
Total Impurities <0.50%    0.10%
Loss on Drying <0.50%    <0.50%   
Residue on Ignition <0.20% <0.20%
Infrared Spectrum Consistent with Structure Complies 
1H NMR Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications
Shelf Life Two Years if Stored Properly 

872728-81-9 - Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. None of the products will be supplied to countries in which this could be in conflict with the existing patents. However the final responsibility lies with the Buyer.

Package/Storage/Shipping:

Package: Bottle, Aluminium foil bag, 1kg/Aluminum tin, 25kg/Drum, or according to customer's requirement.
Storage Condition: May be stored at RT for short-term only. Long-term storage is recommended at 4℃. Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

872728-81-9 - Product Description:

Dabigatran Etexilate Mesylate (Pradaxa Mesylate; BIBR 1048MS) (CAS: 872728-81-9) is an alternative clinical direct thrombin inhibitor and a new type of oral anticoagulant. Its mechanism of action is to inhibit the formation of fibrin through reversible and strong competition to bind to the fibrin specific binding site of thrombin, thereby inhibiting the formation of thrombus.

872728-81-9 - Uses:

Dabigatran Etexilate Mesylate (Pradaxa Mesylate; BIBR 1048MS) (CAS: 872728-81-9) is a clinical direct thrombin inhibitor and a new type of oral anticoagulant. Its mechanism of action is to inhibit the formation of thrombus by inhibiting the formation of fibrin by reversibly and potently competing with the fibrin-specific binding site of thrombin. Dabigatran Etexilate Mesylate is a hematological drug substance; anticoagulant drug; can be used to reduce the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation; Dabigatran Etexilate Mesylate is a new synthetic Direct thrombin inhibitor, a prodrug of dabigatran, is a non-peptide thrombin inhibitor.

872728-81-9 - Mechanism of Action:

Dabigatran Etexilate Mesylate is a prodrug of Dabigatran that is metabolized in the body and converted to the active Dabigatran. Compared with Warfarin, Dabigatran Etexilate Mesylate does not require frequent monitoring of coagulation function and dose adjustment during treatment, and there are fewer interactions between drugs and is not affected by eating, thus improving patients' medication compliance.

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