Empagliflozin Intermediate CAS 915095-94-2 Purity >98.0% (HPLC)

Short Description:

Chemical Name: (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydrofuran 

CAS: 915095-94-2

Purity: >98.0% (HPLC)

Appearance: White to Off-White Powder

Intermediates of Empagliflozin (CAS: 864070-44-0) 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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915095-94-2 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl] phenoxy]tetrahydrofuran (CAS: 915095-94-2) with high quality, intermediates of Empagliflozin (CAS: 864070-44-0). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Empagliflozin Intermediates, Please contact: alvin@ruifuchem.com

915095-94-2 - Chemical Properties:

Chemical Name (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydrofuran 
Synonyms (S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran; (3S)-3-{4-[(2-chloro-5-iodophenyl)methyl]phenoxy}oxolane; Empagliflozin impurity C; Empagliflozin Intermediate1
Stock Status In Stock, Commercial Production  
CAS Number 915095-94-2
Molecular Formula C17H16ClIO2
Molecular Weight 414.67 g/mol
Melting Point 59.0~63.0℃ 
COA & MSDS Available
Place of Origin  Shanghai, China
Product Categories
Intermediates of Empagliflozin (CAS: 864070-44-0)  
Brand Ruifu Chemical

915095-94-2 - Specifications:

Items Specifications  Results
Appearance White to Off-White Powder  Conforms      
Identification HPLC Conforms      
Melting Point 59.0~63.0℃ 60.0~63.0℃
Loss on Drying ≤0.50% 0.4% 
Residue on Ignition ≤0.50% 0.08% 
Heavy Metals (Pb) ≤20ppm <10ppm 
Any Single Impurity ≤0.50% 0.20%
Total Impurities ≤1.00% 0.41%
Purity / Analysis Method >98.0% (HPLC)  99.59% 
Infrared Spectrum Conforms to Structure  Conforms
NMR Spectrum Conforms to Structure  Conforms
Conclusion The product has been tested and complies with the given specifications

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

915095-94-2 - Application:

(3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydrofuran (CAS: 915095-94-2), intermediates of Empagliflozin (CAS: 864070-44-0). On August 1, 2014, the Food and Drug Administration (FDA) officially approved the Empagliflozin for the treatment of type 2 diabetes, to improve and control blood glucose of adults. Empagliflozin is the third SGLT-2 inhibiting drugs approved by FDA. Another two SGLT-2 inhibitor drugs, Canagliflozin and Dapagliflozin, belonging to Johnson Pharmaceuticals, AstraZeneca and Bristol-Myers Squibb respectively, are approved by FDA in November 2013 and January 2014 respectively.  

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