(S)-Sitagliptin N-Boc-Acid Impurity CAS 922178-94-7 Purity >98.0% (HPLC)

Short Description:

Boc-(S)-3-Amino-4-(2,4,5-Trifluorophenyl)butyric Acid

Synonyms: (S)-Sitagliptin N-Boc-Acid Impurity

CAS: 922178-94-7

Assay: >98.0% (HPLC)

Appearance: White Solid

Contact: Dr. Alvin Huang

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Product Detail

Product Tags

922178-94-7 - Description:

Ruifu Chemical is the leading manufacturer of Boc-(S)-3-Amino-4-(2,4,5-Trifluorophenyl)butyric Acid ((S)-Sitagliptin N-Boc-Acid Impurity) (CAS: 922178-94-7) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Please contact: alvin@ruifuchem.com

922178-94-7 - Chemical Properties:

Chemical Name	Boc-(S)-3-Amino-4-(2,4,5-Trifluorophenyl)butyric Acid
Synonyms	(S)-Sitagliptin N-Boc-Acid Impurity; (S)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-Trifluorophenyl)butanoic Acid; (βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-2,4,5-Trifluoro-Benzenebutanoic Acid
Stock Status	In Stock, Commercial Production
CAS Number	922178-94-7
Molecular Formula	C15H18F3NO4
Molecular Weight	333.30 g/mol
Melting Point	123.0~125.0℃
Density	1.292
COA & MSDS	Available
Place of Origin	Shanghai, China
Brand	Ruifu Chemical

922178-94-7 - Specifications:

Items	Specifications	Results
Appearance	White Solid	White Solid
Assay / Analysis Method	>98.0% (HPLC)	98.8%
E.E	>98.0%	99.1%
Specific Rotation [α]20/D	-13.0° ~ -15.0° (C=1, MeOH)	-13.8°
NMR (CDCl3)	Consistent with Structure	Consistent with Structure
Conclusion	The product has been tested and complies with the given specifications

Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

922178-94-7 - Application:

Boc-(S)-3-Amino-4-(2,4,5-Trifluorophenyl)butyric Acid ((S)-Sitagliptin N-Boc-Acid Impurity) (CAS: 922178-94-7) is an impurity of Sitagliptin. Sitagliptin is an orally-bioavailable selective DPP4 inhibitor that was discovered through the optimization of a class of β-aminoacid-derived DPP4 inhibitors. It lowers DPP4 activity in a sustained manner following once daily administration, preserves the circulating levels of intact GIP and GLP1 following meals in both acute and chronic studies and reduces blood glucose levels without significant increases in hypoglycaemia.