Chinese Professional Orlistat - Sorafenib Tosylate CAS 475207-59-1 Purity ≥99.0% (HPLC) API Factory High Quality – Ruifu

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Chinese Professional Orlistat - Sorafenib Tosylate CAS 475207-59-1 Purity ≥99.0% (HPLC) API Factory High Quality – Ruifu Detail:

Commercial Supply Sorafenib Tosylate and Related Intermediates:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methylpicolinamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6

Chemical Name Sorafenib Tosylate
CAS Number 475207-59-1
CAT Number RF-API05
Stock Status In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula C28H24ClF3N4O6S
Molecular Weight 637.03
Solubility Soluble in Methanol, DMSO, DMF
Shipping Conditions Ambient
Brand Ruifu Chemical
Item Specifications
Appearance Light Yellow or White Powder
Identification HPLC
Purity / Analysis Method ≥99.0% (HPLC)
Melting Point 225.0~230.0℃
Heavy Metals ≤10ppm
Loss on Drying ≤0.50%
Residue on Ignition ≤0.20%
Any Single Impurity ≤0.20%
Total Impurities ≤1.00%
Test Standard Enterprise Standard
Usage Sorafenib Tosylate (CAS: 475207-59-1) in the treatment of RCC & HCC

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer’s requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

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Sorafenib Tosylate (CAS: 475207-59-1) is a new type of multi-target antitumor drug, was developed by the German Bayer Pharmaceuticals, and displayed expansive antitumor activity in preclinical animal tests. Sorafenib is available in 200-mg tablets for oral administrationand is used in the treatment of RCC and HCC. Sorafenib Tosylate (CAS: 475207-59-1) can simultaneously affect tumor cells and tumor blood vessels. It has a double antitumor effect: it can block the cell signal transduction pathways mediated by RAF/MEK/ERK to directly inhibit tumor cell growth, while also inhibiting VEGF and platelet derived growth factors (PDGF) receptors to prevent the formation of new tumor blood vessels, thus indirectly inhibiting tumor cell growth.  


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