Cholestyramine CAS 11041-12-6 USP API Factory High Purity
Supply with High Purity and Stable Quality
Chemical Name: Cholestyramine
CAS: 11041-12-6
Cholestyramine in the treatment of type Ⅱa hyperlipoproteinemia
API High Quality, Commercial Production
Chemical Name | Cholestyramine |
Synonyms | Cholestyramine Resin; Colestyramine |
CAS Number | 11041-12-6 |
CAT Number | RF-API23 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C27H47N |
Molecular Weight | 385.66878 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White or Off-White Powder, Odorless or has a slightly amine-like odor, Hygroscopic |
Identification | The infrared absorption spectrum of the sample should be consistent with the reference standard |
pH | 4.0~6.0 |
Dialyzable Quaternary Amine | Should meet the requirements |
Chloride | 13.0%~17.0% (Calculated on the dried basis) |
Loss on Drying | ≤12.0% |
Residue on Ignition | ≤0.10% |
Heavy Metals | ≤20ppm |
Bacterial Count | ≤1000 cfu/g |
Yeast and Mold | ≤100 cfu/g |
Escherichia Coli | Should not be detected |
Live Mite Test | Should not be detected |
Purity | Calculated on the dried basis, each g exchanges 2.0g~2.4g of Sodium Taurocholate |
Test Standard | United States Pharmacopeia (USP) |
Usage | Active Pharmaceutical Ingredient (API) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Cholestyramine (CAS: 11041-12-6) with high quality, active pharmaceutical ingredient (API). Cholestyramine (Colestyramine) is a bile acid binding resin and can inhibit intestinal bile acid absorption which results in the increasing bile acid synthesis from cholesterol. A strongly basic anion exchange resin whose main constituent is polystyrene trimethylbenzylammonium Cl(-) anion.
Cholestyramine: it is mainly used for the treatment of type Ⅱa hyperlipoproteinemia, especially in familial hypercholesterolemia. Also it is used for the treatment of primary biliary cirrhosis, drug-induced cholestatic jaundice itching, hypercholesterolemia, chronic cholecystitis, gallstones, Porphyrin thesaurismosis. Treatment of Atherosclerosis: 4~5g, 3 times/d. Itching: Start amount of 6~10g/d, maintenance dose of 3g/d, administration for 3 times. Long-term use can reduce intestinal binding bile salt, and cause fat malabsorption, long-term use should add vitamin A, D, K and other fat-soluble vitamins and calcium appropriately, gastrointestinal responders may be appropriate with stomach medication.