(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2 Atazanavir Intermediate High Purity

Short Description:

Name: (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane

(2S,3S)-3-(Boc-Amino)-1,2-Epoxy-4-Phenylbutane

CAS: 98737-29-2

Appearance: White to Off-White Crystalline Powder

Purity: ≥99.0% (HPLC) Chiral Impurity: ≤0.30%

Intermediate of Atazanavir HIV-1 Protease Inhibitor

High Quality, Commercial Production

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Product Detail

Product Tags

Description:

Manufacturer Supply Atazanavir Related Intermediates
Moc-L-Tert-Leucine CAS 162537-11-3
4-(2-Pyridyl)benzaldehyde CAS 127406-56-8
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate CAS 198904-85-7
Atazanavir CAS 198904-31-3
Atazanavir Sulfate CAS 229975-97-7

Chemical Properties:

Chemical Name	(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane
Synonyms	(2S,3S)-3-(Boc-Amino)-1,2-Epoxy-4-Phenylbutane; (2S,3S)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane; Darunavir Intermediate
CAS Number	98737-29-2
CAT Number	RF-PI286
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C15H21NO3
Molecular Weight	263.33
Solubility	Insoluble in Water. Soluble in Methanol, Chloroform
Shipping Condition	Shipped Under Ambient Temperature
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White to Off-White Crystalline Powder
Identification (HPLC)	The Identification is Confirmed by HPLC
Melting Point	123.0~128.0℃
Moisture (K.F)	≤0.50%
Residue on Ignition	≤0.20%
Purity / Analysis Method	≥99.0% (HPLC)
Chlorohydrin (HPLC)	≤0.20%
Chloromethyl Ketone	≤0.10%
Other Single Impurity	≤0.20%
Total Impurities	≤1.0%
Chiral Impurity	≤0.30%
Heavy Metals	≤20ppm
Test Standard	Enterprise Standard
Usage	Intermediate of Darunavir (CAS 206361-99-1) HIV-1 Protease Inhibitor

Package & Storage:

Package: Bottle, Aluminium foil bag, Cardboard Drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

FAQ:

Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of (2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane (CAS: 98737-29-2) with high quality, an intermediate typically in the synthesis of Atazanavir (CAS 198904-31-3) and Atazanavir Sulfate (CAS 229975-97-7).

Atazanavir is a highly potent HIV-1 protease inhibitor. Has shown to be generally more potent than the five currently approved HIV-1 Prt inhibitors. Atazanavir (BMS-232632) inhibited the proteolytic cleavage of the viral gag precursor p55 polyprotein in a dose-dependent manner, with a EC 50 of approximately 47 nM. Also highly selective for HIV-1 Prt and exhibits cytotoxicity only at concentrations 6,500- to 23,000-fold higher than that required for anti-HIV activity. Atazanavir (BMS-232632) may be an effective HIV-1 inhibitor that may be utilized in a variety of different drug combinations.