D-(-)-2-Phenylglycine Methyl Ester Hydrochloride CAS 19883-41-1 Purity >98.5% (HPLC)

Short Description:

D-(-)-2-Phenylglycine Methyl Ester Hydrochloride

Synonyms: H-D-Phg-OMe·HCl 

CAS: 19883-41-1

Purity: >98.5% (HPLC)

Appearance: White to Off-White Crystalline Powder 

Unnatural Amino Acids Derivatives, High Quality 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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19883-41-1 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of D-(-)-2-Phenylglycine Methyl Ester Hydrochloride (H-D-Phg-OMe·HCl) (CAS: 19883-41-1) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase H-D-Phg-OMe·HCl, Please contact: alvin@ruifuchem.com

19883-41-1 - Chemical Properties:

Chemical Name D-(-)-2-Phenylglycine Methyl Ester Hydrochloride 
Synonyms H-D-Phg-OMe·HCl; H-D-Phg-OMe Hydrochloride; D-Phenylglycine Methyl Ester HCl; D-(-)-α-Phenylglycine Methyl Ester Hydrochloride; (R)-(-)-2-Phenylglycine methyl ester hydrochloride; Methyl (R)-(-)-2-Amino-2-Phenylacetate Hydrochloride; (R)-(-)-2-Amino-2-Phenylacetic Acid Methyl Ester Hydrochloride; Methyl (2R)-Amino(phenyl)ethanoate; (R)-(-)-alpha-Aminophenylacetic Acid Methyl Ester Hydrochloride
Stock Status In Stock, Production Capacity 2500 Tons per Year
CAS Number 19883-41-1
Molecular Formula C9H11NO2·HCl 
Molecular Weight 201.65 g/mol
Melting Point 205.0~215.0℃ 
Solubility (Soluble in ) Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
COA & MSDS Available
Origin of Product    Shanghai, China
Shelf Life 2 Years When Properly Stored
Product Categories
Pharmaceutical Intermediates
Brand Ruifu Chemical

19883-41-1 - Specifications:

Items Specifications  Results
Appearance White to Off-White Crystalline Powder  Off-White Crystalline Powder  
Melting Point 205.0~215.0℃ 210.0~212.0℃
Specific Rotation [a]20/D  -133.0° ~ -135.0° (C=2 in MeOH) -134.2°
Loss on Drying <0.50% 0.13%
Iron (Fe) <5ppm <5ppm
H-D-Phg-OMe·HCl Purity >98.5% (HPLC)  99.36%
Infrared Spectrum Consistent with Structure Complies
Conclusion The product has been tested and complies with the given specifications

19883-41-1 - Package/Storage/Shipping:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/paper bag with double-layer PE inner bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery. 

19883-41-1 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

19883-41-1 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

19883-41-1 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes 36 - Irritating to the eyes
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
WGK Germany 3
HS Code 2922491990

19883-41-1 - Application:

D-(-)-2-Phenylglycine Methyl Ester Hydrochloride (H-D-Phg-OMe·HCl) (CAS: 19883-41-1) is commonly used in the pharmaceutical industry, is an important antibiotic intermediate, which is mainly used to synthesize Cefaclor, Ampicillin, Piperacillin, Cephalexin, Cephradine and so on.
H-D-Phg-OMe·HCl is an intermediate in the synthesis of Cephradine, a cephalosporin antibiotic. It functions as an acyl donor in the enzymatic synthetic process for cephradine synthesis.
Cefaclor and Ampicillin are semi-synthetic second-generation cephalosporins with antibacterial spectrum and antibacterial activity similar to cefazolin. They are mainly used in the treatment of otitis media, lower respiratory tract infection, urinary tract infection, skin and skin tissue infection, and can inhibit all haemophilus influenzae bacteria. Including strains resistant to ampicillin. Although the process reported in the synthesis patent is simple, the final product is D-phenylglycine methyl ester hydrochloride, and the synthesis of cephalox and ampicillin requires desalination, which brings cumbersome processes to the subsequent synthesis, so the free D-phenylglycine methyl ester can be obtained at low cost and has commercial value.  

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