D-(-)-2-Phenylglycine Methyl Ester Hydrochloride CAS 19883-41-1 Purity >98.5% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of D-(-)-2-Phenylglycine Methyl Ester Hydrochloride (H-D-Phg-OMe·HCl) (CAS: 19883-41-1) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase H-D-Phg-OMe·HCl, Please contact: alvin@ruifuchem.com
Chemical Name | D-(-)-2-Phenylglycine Methyl Ester Hydrochloride |
Synonyms | H-D-Phg-OMe·HCl; H-D-Phg-OMe Hydrochloride; D-Phenylglycine Methyl Ester HCl; D-(-)-α-Phenylglycine Methyl Ester Hydrochloride; (R)-(-)-2-Phenylglycine methyl ester hydrochloride; Methyl (R)-(-)-2-Amino-2-Phenylacetate Hydrochloride; (R)-(-)-2-Amino-2-Phenylacetic Acid Methyl Ester Hydrochloride; Methyl (2R)-Amino(phenyl)ethanoate; (R)-(-)-alpha-Aminophenylacetic Acid Methyl Ester Hydrochloride |
Stock Status | In Stock, Production Capacity 2500 Tons per Year |
CAS Number | 19883-41-1 |
Molecular Formula | C9H11NO2·HCl |
Molecular Weight | 201.65 g/mol |
Melting Point | 205.0~215.0℃ |
Solubility (Soluble in ) | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
COA & MSDS | Available |
Origin of Product | Shanghai, China |
Shelf Life | 2 Years When Properly Stored |
Product Categories |
Pharmaceutical Intermediates |
Brand | Ruifu Chemical |
Items | Specifications | Results |
Appearance | White to Off-White Crystalline Powder | Off-White Crystalline Powder |
Melting Point | 205.0~215.0℃ | 210.0~212.0℃ |
Specific Rotation [a]20/D | -133.0° ~ -135.0° (C=2 in MeOH) | -134.2° |
Loss on Drying | <0.50% | 0.13% |
Iron (Fe) | <5ppm | <5ppm |
H-D-Phg-OMe·HCl Purity | >98.5% (HPLC) | 99.36% |
Infrared Spectrum | Consistent with Structure | Complies |
Conclusion | The product has been tested and complies with the given specifications |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/paper bag with double-layer PE inner bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Symbols Xi - Irritant
Risk Codes 36 - Irritating to the eyes
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
WGK Germany 3
HS Code 2922491990
D-(-)-2-Phenylglycine Methyl Ester Hydrochloride (H-D-Phg-OMe·HCl) (CAS: 19883-41-1) is commonly used in the pharmaceutical industry, is an important antibiotic intermediate, which is mainly used to synthesize Cefaclor, Ampicillin, Piperacillin, Cephalexin, Cephradine and so on.
H-D-Phg-OMe·HCl is an intermediate in the synthesis of Cephradine, a cephalosporin antibiotic. It functions as an acyl donor in the enzymatic synthetic process for cephradine synthesis.
Cefaclor and Ampicillin are semi-synthetic second-generation cephalosporins with antibacterial spectrum and antibacterial activity similar to cefazolin. They are mainly used in the treatment of otitis media, lower respiratory tract infection, urinary tract infection, skin and skin tissue infection, and can inhibit all haemophilus influenzae bacteria. Including strains resistant to ampicillin. Although the process reported in the synthesis patent is simple, the final product is D-phenylglycine methyl ester hydrochloride, and the synthesis of cephalox and ampicillin requires desalination, which brings cumbersome processes to the subsequent synthesis, so the free D-phenylglycine methyl ester can be obtained at low cost and has commercial value.