D-Serine CAS 312-84-5 H-D-Ser-OH Assay 99.0~101.0% Factory High Quality

Acidity pH
Take 0.30g of this product, add 30ml of water to dissolve, and measure according to law (General rule 0631). The pH value should be 5.5~6.5.
Transmittance of Solution
take 1.0g of this product, add water 20ml to dissolve, according to ultraviolet-visible spectrophotometry (General rule 0401), determine the transmittance at the wavelength of 430mn, not less than 98.0%.
Chloride
Take 0.25g of this product and check it according to law (General rule 0801). Compared with the control solution made of 5.0 ml of standard sodium chloride solution, it should not be more concentrated (0.02%).
Sulfate
Take 1.0g of this product and check it according to law (General rule 0802). Compared with the control solution made of 2.0 ml of standard potassium sulfate solution, it should not be more concentrated (0.02%).
Ammonium Salt
take 0.10g of this product and check it according to law (General rule 0808). Compared with the control solution made of 2.0 ml of standard ammonium chloride solution, it shall not be deeper (0.02%).
Other Amino Acids
Take an appropriate amount of this product, add water to dissolve and dilute to make a solution containing about 20mg per lml as a test solution; Take 1ml for precision measurement and put it in a 200ml measuring flask, dilute to the scale with water, shake well, as a control solution; Take the appropriate amount of serine reference and methionine reference respectively, and place in the same measuring flask, water was added to dissolve and diluted to prepare a solution containing about 0.4mg each per 1ml as a system-suitable solution. According to the thin layer chromatography (General 0502) test, absorb the above three solutions each 5 u1, respectively, on the same silica gel G thin layer plate, with n-butanol-water-glacial acetic acid (3:1:1) for development, after deployment, air-drying, spraying with ninhydrin in acetone solution (1-50), heating at 80°C until spots appear, and examination immediately. The control solution should show a clear spot, and the system applicable solution should show two completely separated spots. If the test solution shows impurity spots, the color should not be deeper (0.5%) than the main spot of the control solution.
Loss on Drying
take this product, dry at 105℃ for 3 hours, loss of weight shall not exceed 0.2% (General rule 0831).
Residue on Ignition
Not more than 0.1% (General rule 0841).
Iron Salt
Take 1.0g of this product and check it according to law (General rule 0807). Compared with the control solution made of 0.001% of standard iron solution, it shall not be deeper ().
Heavy Metals
Take 2.G of this product, add 23ml of water to dissolve, add 2ml of acetate buffer (pH3.5), and check according to law (the first law of the general rules 0821), containing heavy metals shall not exceed 10 parts per million.
Arsenic Salt
Take this product 2. G, add water 23ml dissolved, add hydrochloric acid 5ml, according to the law inspection (General Principles 0822 first law), should comply with the provisions (0.0001%).
Bacterial Endotoxin
Take this product, check according to law (General 1143), the amount of endotoxin in each lg serine should be less than 12EU. (For injection)
312-84-5 - Content Determination
Take this product about 0.1g, precision weighing, add anhydrous formic acid 1 ml to dissolve, add glacial acetic acid 25ml, according to the potentiometric titration method (General 0701), with perchloric acid titration solution (0.1 mol/L) titration, and the results of the titration were corrected with a blank test. Each 1 ml of perchloric acid titration solution (0.1 mol/L) corresponds to 10.51 mg of C3H7N03.