Dess-Martin Periodinane CAS 87413-09-0 (DMP) Assay >98.0% (Base on Theoxidation) Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Dess-Martin Periodinane (DMP) (CAS: 87413-09-0) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase Dess-Martin Periodinane, Please contact: alvin@ruifuchem.com
| Chemical Name | Dess-Martin Periodinane |
| Synonyms | DMP; Martin's Reagent; Dess-Martin Reagent; 1,1,1-Triacetoxy-1,1-Dihydro-1,2-Benziodoxol-3(1H)-one; Triacetoxyperiodinane |
| Stock Status | In Stock, Production Capacity 6 Tons per Month |
| CAS Number | 87413-09-0 |
| Molecular Formula | C13H13IO8 |
| Molecular Weight | 424.14 g/mol |
| Melting Point | 130.0~133.0℃(lit.) |
| Density | 1.369 g/mL at 25℃ |
| Sensitive | Air Sensitive, Moisture Sensitive, Heat Sensitive |
| Solubility | Soluble in Chloroform, Acetone, Acetonitrile and Methylene Chloride. Slightly Soluble in Ether and Hexane. |
| Storage Temp. | Cool & Dry Place (2~8℃) (Refrigerate) |
| COA & MSDS | Available |
| Categories | Oxidizing Reagents; Hypervalent Iodine Compounds |
| Brand | Ruifu Chemical |
| Items | Inspection Standards | Results |
| Appearance | White Powder, Grain | Complies |
| Melting Range | 130.0~133.0℃ | 131.1~132.6℃ |
| Assay / Analysis Method | >98.0% (Base on Theoxidation) | 99.3% |
| NMR Spectrum | Conforms to Structure | Complies |
| Storage | Preserve in Tight, Light-Resistant Containers | |
| Conclusion | The product has been tested & complies with the given specifications | |
Package: Bottle, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Preserve in tight, light-resistant containers. Protect from light, moisture and heat.
Shipping: Deliver to worldwide by FedEx / DHL Express. Provide fast and reliable delivery.
Risk Codes
R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
R40 - Limited evidence of a carcinogenic effect
R8 - Contact with combustible material may cause fire
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R44 - Risk of explosion if heated under confinement
Safety Description
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S36/37 - Wear suitable protective clothing and gloves.
S24/25 - Avoid contact with skin and eyes.
S23 - Do not breathe vapour.
S17 - Keep away from combustible material.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs UN 1593 6.1/PG 3
WGK Germany 3
TSCA No
HS Code 29349990
Hazard Note Harmful / Light sensitive
Hazard Class 5.1
Packing Group Ⅲ
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Dess-Martin Periodinane (DMP) (CAS: 87413-09-0), hypervalent iodine reagent, is a commonly used, mild, and selective oxidation reagent. Its advantages are mild reaction conditions, moderate speed, less dosage and simple post-treatment.
Dess-Martin Periodinane is a very useful reagent used in the oxidation of primary alcohols to aldehydes and secondary alcohols to ketones. Dess-Martin Periodinane is also used as an oxidant for complexes with multifunctional alcohols. It is actively involved in the oxidation of N-protected-amino alcohols without epimerization and allylic alcohols.
The Dess-Martin Periodinane is a mild, versatile reagent for selective oxidation of primary and secondary alcohols to aldehydes and ketones, hydroxamic acids to acyl notroso compounds, deprotection of thioacetals, deoximation of ketoximes to ketones.
In recent years, organic high iodine compounds as a kind of easy preparation, mild performance, new reagents for organic synthesis, which are highly selective and environmentally friendly, are widely used in modern organic synthesis. Dess-Martin Periodinane is one of the most studied and most widely used reagents.
2-Iodobenzoic Acid (50.0g, 0.20mol) was added to sulfolane (250mL), the solution was heated to 50℃. 90% of the above solution was slowly added dropwise to an aqueous solution (147.4 ml) of potassium hydrogen persulfate (0.24g, 1.2 mol, eq) at 50℃, and the reaction was incubated for 3 hours. Subsequently, the reaction solution was heated to 95℃. And the remaining 10% 2-iodobenzoic acid solution was slowly added dropwise to the reaction solution, and the reaction was continued for 3 hours. After completion of the reaction, it was cooled to 5℃ and stirring was continued at this temperature for 1.5 hours. 1L of water was added with stirring and filtered (the filtrate was to be recycled). The filter cake was rinsed with water and acetone successively and dried at room temperature for 16 hours to obtain 53.2g of 2-iodoylbenzoic acid (yield: 95.04%), white solid with 99.7% purity (confirmed by NMR and HPLC). Detected by HNMR, The solid was determined to be 2-iodoylbenzoic acid. 2-iodoylbenzoic acid (45g, 0.16mol) was added to acetic anhydride (49G, 0.48mol) and dioxane (90ml), followed by B(C6F5)3 (0.0016mol), the reaction solution was heated to 50℃. And stirred for 10 minutes, and then the solvent was distilled off under reduced pressure. The reaction solution was added with methyl tert-butyl ether (400mL), suction filtered, and dried at room temperature to obtain a white solid (61.1g, yield: 90%). The purity was 99.1% (confirmed by NMR).
