DL-2-(2-Chlorophenyl)glycine CAS 141196-64-7 Assay ≥98.5% High Purity Clopidogrel Intermediate

Short Description:

Chemical Name: DL-2-(2-Chlorophenyl)glycine 

Synonyms: H-DL-Phg(2-Cl)-OH

CAS: 141196-64-7

Appearance: White to Off-White Powder

Assay: ≥98.5%

Intermediate of Clopidogrel (CAS: 113665-84-2)

High Quality, Commercial Production


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Description:

Supply with High Purity and Stable Quality
Chemical Name: DL-2-(2-Chlorophenyl)glycine
Synonyms: H-DL-Phg(2-Cl)-OH
CAS: 141196-64-7 
High Quality, Commercial Production

Chemical Properties:

Chemical Name DL-2-(2-Chlorophenyl)glycine
Synonyms H-DL-Phg(2-Cl)-OH
CAS Number 141196-64-7
CAT Number RF-CC254
Stock Status In Stock 
Molecular Formula C8H8ClNO2
Molecular Weight 185.61
Refractive Index 1.603
Density 1.392g/cm3
Shipping Condition Shipped Under Ambient Temperature
Brand Ruifu Chemical

Specifications:

Item Specifications
Appearance White to Off-White Powder
Loss on Drying ≤1.0%
Melting Point 195.0~203.0℃
Chlorides ≤1000mg/kg
Acid Solubility Test Qualified
Assay ≥98.5%
Test Standard Enterprise Standard
Usage Clopidogrel Intermediate; Pharmaceutical Intermediate

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

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FAQ:

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Application:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of DL-2-(2-Chlorophenyl)glycine (CAS: 141196-64-7) with high quality, widely used in organic synthesis, synthesis of pharmaceutical intermediates and active pharmaceutical ingredient (API) synthesis. 

DL-2-(2-Chlorophenyl)glycine (CAS: 141196-64-7) is an intermediate typically in the synthesis of Clopidogrel (CAS: 113665-84-2), API.

Clopidogrel was launched in the US as a potent inhibitor of platelet aggregation for the preventive management of secondary ischemic events, including MI, stroke and vascular deaths. Clopidogrel can be synthesized in 4 steps (including an optical resolution to the S active enantiomer) from DL-2-(2-Chlorophenyl)glycine (CAS: 141196-64-7), the key step being the cyclization to thienopyridine with formaldehyde and acetic acid. Unlike other thienopyridinescurrently used, clopidogrel does not seriously reduce thenumber of white cells in the blood, and therefore, routinemonitoring of the white blood cell count is not necessaryduring treatment. 

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