DL-Methionine CAS 59-51-8 (H-DL-Met-OH) Assay 99.0~101.0% Factory High Quality

Short Description:

Chemical Name: DL-Methionine

Synonyms: H-DL-Met-OH; (±)-Methionine 

CAS: 59-51-8  

Assay: 99.0~101.0% (on Dried Basis) 

Appearance: White Crystals or Crystalline Powder; Sweet and Slightly Bitter Taste 

Amino Acids & Derivatives, Large Scale Production 

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of DL-Methionine (H-DL-Met-OH) (CAS: 59-51-8) with high quality, production capacity 1000 Tons per year. Ruifu Chemical supplys a series of amino acids & derivatives. We can provide COA, worldwide delivery, small and bulk quantities available. If you are interested in DL-Methionine, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name DL-Methionine 
Synonyms H-DL-Met-OH; Dextro, Laevo-Methionine; (±)-Methionine; (±)-2-Amino-4-(Methylmercapto)butyric Acid; DL-2-Amino-4-(Methylthio)butanoic Acid; (±)-2-Amino-4-(Methylthio)butyric Acid; (2RS)-2-Amino-4-(Methylsulfanyl)butanoic Acid
Stock Status In Stock, Production Capacity 1000 Tons per Year 
CAS Number 59-51-8  
Molecular Formula C5H11NO2S 
Molecular Weight 149.21  
Melting Point 270.0~280.0℃(dec.)(lit.)
Boiling Point 306.9±37.0℃
Density 1.340 g/ml 
Sensitive Light Sensitive
Solubility in Hot Water Almost Transparency
Solubility  Soluble in 5M HCl (100 mg/ml), Water (56.6 mg/ml at 25℃), Acetic Acid, and Warm Dilute Alcoho. Insoluble in Ether, Acetone, Benzene 
Storage Temp.  Sealed in Dry, Store at Room Temperature
COA & MSDS Available
Classification Amino Acids & Derivatives
Brand Ruifu Chemical

Safety Information:

Hazard Codes Xi  RTECS  PD0457000  
Risk Statements 33-36/37/38  F    10-23   
Safety Statements    24/25-36-26            TSCA                     Yes
WGK Germany 2   HS Code           2930400000                      

Specifications:

Items Inspection Standards Results
Appearance White Crystals or Crystalline Powder Conforms          
Identification Infrared Absorption Spectrum Conforms
Specific Rotation [α]20/D -1.0° to +1.0°(C=8, HCl)
Conforms 
State of Solution (Transmittance) Clear and Colorless ≥98.0% 99.52%
Chloride (Cl) ≤0.020% <0.020%
Sulfate (SO4) ≤0.020% <0.020%
Ammonium (NH4) ≤0.020% <0.020%
Iron (Fe) ≤10ppm <10ppm
Heavy Metals (Pb) ≤10ppm <10ppm 
Arsenic (As2O3) ≤1.0ppm <1.0ppm
Other Amino Acids Conforms  Conforms
Loss on Drying ≤0.30% 0.16%
Residue on Ignition (Sulfated) ≤0.10% 0.04%
Assay 99.0 to 101.0% (on Dried Basis)      99.7%
pH Value 5.6 to 6.1 (1.0g in 100ml of H2O) 5.8
Conclusion Meets with the Spectifications of AJI97, EP
Main Uses Food / Feed Additives; Pharmaceuticals

Test Method:

DL-Methionine (H-DL-Met-OH) (CAS: 59-51-8) AJI 97 Test Method
Identification: Compare the infrared absorption spectrum of the sample with that of the standard by potassium bromide disc method.
State of Solution (Transmittance): 0.5g in 20ml of H2O, spectrophotometer, 430nm, 10mm cell thickness.
Chloride (Cl): 0.7g, A-4, ref: 0.40ml of 0.01mol/L HCl
Ammonium (NH4): A-2
Sulfate (SO4): 1.2g, (1), ref: 0.50ml of 0.005mol/L H2SO4
Iron (Fe): 1.5g, ref: 1.50ml of Iron Std. (0.01mg/ml)
Heavy Metals (Pb): 2.0g, dissolve by warming, ref: 2.0ml of Pb Std. (0.01mg/ml)
Arsenic (As2O3): 2.0g, (1), ref: 2.0ml of As2O3 Std.
Other Amino Acids: Test Sample: 50μg, B-1-a, control; DL-Met 0.25μg
Loss on Drying: at 105℃ for 4 hours.
Residue on Ignition (Sulfated): AJI Test 13
Assay: Dried sample, 150mg, (1), 3ml of formic acid, 50ml of glacial acetic acid, 0.1mol/L HCLO4 1ml=14.921mg C5H11NO2S
pH Test: 1.0g in 100ml of H2O

DL-Methionine (H-DL-Met-OH) (CAS: 59-51-8) EP8.0 Test Method
DEFINITIOND L-Methionine contains not less than 99.0 per centand not more than the equivalent of 101.0 percent of (2RS)-2-Amino-4-(Methylsulfanyl)butanoic Acid, calculated with reference to the dried substance.
CHARACTERS Almost white, crystalline powder or small flakes, sparingly soluble in water, very slightly soluble in alcohol. It dissolves indilute acids and in dilute solutions of the alkali hydroxides. It melts at about270℃ (instantaneous method)
IDENTIFICATION
First identification: A, C.
Second identification: B,C,D
A. Examine by infrared absorption spectrophotometry (2.2.24), comparing with the spectrum obtained with DL-Methionine CRS. Dry the substances at 105℃
B. Examine the chromatograms obtained in the test for related substances. The principal spot in the chromatogram obtained with test solution (b) is similar in position, colour and size to the principal spot in the chromatogram obtained with reference solution (a).
C. Dissolve 2.50 g in1 M hydrochloric acid and dilute to 50.0mL with the same acid. The angle of optical rotation (2.2.7) is - 0.05° to + 0.05°.
D. Dissolve 0.1 g of the substance to be examined and 0.1 g of glycine R in 4.5 mL of dilute sodium hydroxide solution R. Add 1 mL of a 25 g/L solution of sodium nitroprusside R. Heat to 40℃ for 10min. Allow to cool and add 2mL of a mixture of 1 volume of phosphoric acid R and 9 volumes of hydrochloric acid R. A deep-red colour develops.
TESTS
Solution S. Dissolve 1.0 g in carbon dioxide-free water R and dilute to 50 mL with the same solvent.
Appearance of solution. Solution S is clear (2.2.1) and colourless (2.2.2, Method II).
pH(2.2.3). The pH of solution S is 5.4 to 6.1.

Package & Storage:

Package: Aluminium foil bag, 25kg/bag, 25kg/Cardboard Drum, or according to customer's requirement. 

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Storage Condition: Store in sealed containers at cool, dry and ventilated warehouse away from incompatible substances. Protect from light and moisture. 

Stability: Stable. Incompatible with strong oxidising agents.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

Application:

DL-Methionine (H-DL-Met-OH) (CAS: 59-51-8) is is one of the basic units for composing the protein, is the only sulfur bearing amino acid among the essential amino acids, it participated in the transmethylation interior the animal body, the phosphorus metabolism and the adrenalin, choline and creatine synthesis, it also is the raw material of the protein and cystine synthesis. Methionine is unable to synthesize in the animal body, must take in from food. Adds it in the feed, can promote the poultry to grow, increase lean meat quantity and reduce the feeding cycle.
Application of Dl-Methionine
{Feed Grade}
Animal feed supplement for livestock is chelated by DL-Methionine and zinc sulphat.
1. Resulting from the reaction of a mole of zinc ion to a moles of methionine, high chelate percentage, the greatest stability.
2. High bioavailability, better nutrition of zinc, is a kind of better feed additive.
3. Don't be affected by pH value, inorganic ions and organic macromolecules in digestive tract.
Product function
Be added to animal feeds, DL-Methionine can help animals grow quickly in a short time and about 40% of their feed can be saved.
1. The bioavailability of animal feed supplement for livestock significantly better than other organic zinc.
2. Solve the problem of hoof crack for sows efficiently .
3. Increase the laying, fertilization, and hatching rates, improve the quality of eggshell.
4. Leads to the removal of rough and messy feather, obtaining bright feather. And decrease in cannib alism of pecking the plume and anus.
5. Increase feed intake effectively, can improve animal growth and the resistance of disease, promote more nutrition.
6. This zinc methionine can suplement animals nore nutrition healthy, can make the animals growth.
{Food Grade}
DL-Methionine is one of the 18 common amino acids, and one of the eight essential amino acids at the animal and human body. It is mainly used as feed additives in fish, chickens, pigs and cows meal in order to keep animal and fowl growing healthily. It can improve the milk secretion of cows, prevent the occurrence of hepatosis. Besides, it can also be used as amino acid medicines, injection solution, a nutritional infusion, the agent of protective liver, the therapy liver cirrhosis and toxic hepatitis.
1. DL-Methionine can be used in the synthesis of medicinal vitamins, nutritional supplements and feed additives.
2. DL-Methionine is one of the main components of amino acid infusion and compound amino acid. DL-Methionine has anti-fatty liver function. Taking advantage of this function, the synthetic medicinal vitamins can be used as liver protection preparations.
3. As essential amino acid of the human body, DL-Methionine can be used as a nutritional supplement in food and preservative processing such as fish cake products.
4. As an important component in protein synthesis, DL-Methionine has a protective effect on the heart muscle. At the same time, DL-Methionine can be converted into Taurine by sulfur, while Taurine has a very obvious hypotensive effect. DL-Methionine also has a good function for liver protection and detoxification, so it is commonly used in clinical treatment of liver diseases such as cirrhosis, fatty liver and various acute and chronic viral hepatitis. It has a very good effect.
5. DL-Methionine can be used as nutional supplement. DL-Methionine has the same effect with L-Methionine, but DL-Methionine is cheaper.
6. DL-Methionine can be formulated as a flavoring agent.
7. DL-Methionine is the feed nutrition enhancer. Livestock and poultry lack of Methionine, can lead to stunted growth, weight loss, liver and kidney function abate, muscle atrophy, fur, metamorphism and so on. Add 1 kg Methionine, feed of 50 kg fish meal nutrition value. Feed in the general content of 0.05% to 0.2%.  

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