Entecavir CAS 142217-69-4 API Factory High Quality Anti-HBV

Short Description:

Name: Entecavir

CAS: 142217-69-4

Appearance: White Crystalline Powder

Antiviral drug used in the treatment of Hepatitis B Infection

API High Quality, Commercial Production

Inquiry: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Manufacturer Supply with High Purity and Stable Quality
Chemical Name: Entecavir
CAS: 142217-69-4
Antiviral drug used in the treatment of Hepatitis B Infection
API High Quality, Commercial Production

Chemical Properties:

Chemical Name	Entecavir
Synonyms	2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
CAS Number	142217-69-4
CAT Number	RF-API80
Stock Status	In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula	C12H15N5O3
Molecular Weight	277.28
Melting Point	249.0~252.0℃
Brand	Ruifu Chemical

Specifications:

Item	Specifications
Appearance	White Crystalline Powder
Identification IR	The infraed absorption spectrum of the test sample must be concordant with the reference standard
Identification HPLC	The retention time of the test sample corresponds to that of the reference standard
pH	5.5~7.5
Specific Optical Rotation	+24.0°-+28.0° (DMF: MeOH=1:1 C=1%)
Related Substances
Total Impurities	≤0.30%
Maximum Single Impurity	≤0.10%
Enantiomer	≤0.20%
Residual Solvents
Methanol	≤0.30%
Dichloromethane	≤0.06%
n-Hexane	≤0.029%
Tetrahydrofuran	≤0.072%
N,N-Dimethylformamide	≤0.088%
Toluene	≤0.089%
Water Content	5.8%~6.5%
Residue on Ignition	≤0.10%
Heavy Metals	≤20ppm
Assay	98.0%~102.0% (C12H15N5O3 calculated on anhydrous basis)
Particle Size	D90: ≤100µm
Test Standard	Enterprise Standard
Usage	API, Antiviral drug used in the treatment of Hepatitis B Infection

Package & Storage:

Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.

Advantages:

FAQ:

Application:

Entecavir is a new generation of guanine nucleoside analogues oral medicine for treatment of Hepatitis B Virus (HBV) infection, mainly for the treatment of adult patients with viral replication activity and serum transaminase continued to increase, or liver tissue for pathological activity of chronic hepatitis B, is currently down virus the fastest and the most powerful, the mutation rate lowest nucleoside analogues. Data show that different in patients with chronic hepatitis B, including nucleoside naive and nucleoside treated and liver cirrhosis patients, using well entecavir tablets in the treatment can control the disease rapidly and easily reach the treatment of reality end, namely the hepatitis B virus unmeasured; through adherence to treatment, a considerable portion of patients can be arrived at the end of treatment satisfaction, namely e antigen serology conversion, some patients can even reach the ideal for the treatment of end, namely surface antigen negative.