Ethyl 7-Chloro-2-Oxoheptanoate CAS 78834-75-0 Purity >98.0% (GC) Cilastatin Sodium Intermediate

Short Description:

Chemical Name: Ethyl 7-Chloro-2-Oxoheptanoate

Synonyms: 7-Chloro-2-Oxoheptanoic Acid Ethyl Ester

CAS: 78834-75-0

Purity: >98.0% (GC)

Pale Green to Light Yellow Transparent Liquid

Intermediate of Cilastatin Sodium (CAS: 81129-83-1)

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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78834-75-0 - Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Ethyl 7-Chloro-2-Oxoheptanoate (CAS: 78834-75-0) with high quality, intermediate of Cilastatin Sodium (CAS: 81129-83-1). Imipenem and Cilastatin combination is used to treat a wide variety of bacterial infections. This medication is known as a carbapenem-type antibiotic.
Ruifu Chemical has been supplying pharmaceutical intermediates and APIs, fine chemicals more than 15 years.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Cilastatin Sodium intermediates, please contact us by e-mail: alvin@ruifuchem.com

Intermediates of Cilastatin Sodium:

Cilastatin Sodium	CAS 81129-83-1
Ethyl 7-Chloro-2-Oxoheptanoate	CAS 78834-75-0
(S)-(+)-2,2-Dimethylcyclopropanecarboxamide	CAS 75885-58-4
(S)-(+)-2,2-Dimethylcyclopropanecarboxylic Acid	CAS 14590-53-5
L-Cysteine Hydrochloride Monohydrate	CAS 7048-04-6

78834-75-0 - Chemical Properties:

Chemical Name	Ethyl 7-Chloro-2-Oxoheptanoate
Synonyms	7-Chloro-2-Oxoheptanoic Acid Ethyl Ester; ECO
Stock Status	In Stock, Commercial Production
CAS Number	78834-75-0
Molecular Formula	C9H15ClO3
Molecular Weight	206.67 g/mol
Flash Point	113℃
Specific Gravity (20/20)	1.110 g/ml
Refractive Index n20/D	1.45
Store Under Inert Gas	Store Under Inert Gas
Sensitive	Air Sensitive, Heat Sensitive
Storage Temperature	Store Long-Term at 2-8℃
COA & MSDS	Available
Origin of Product	Shanghai, China
Product Categories	Pharmaceutical Intermediates
Brand	Ruifu Chemical

78834-75-0 - Specifications:

Items	Specifications	Results
Appearance	Pale Green to Light Yellow Transparent Liquid	Conforms
Water by Karl Fischer	<0.50%	0.36%
Specific Gravity	1.105-1.110	Conforms
Refractive Index n20/D	1.451-1.456	Conforms
Purity / Analysis Method	>98.0% (GC)	98.19%
1H NMR Spectrum	Conforms to Structure	Conforms
Conclusion	The product has been tested and complies with the given specifications
Application	Intermediate of Cilastatin Sodium (CAS: 81129-83-1)

78834-75-0 - Package/Storage/Shipping:

Package: Fluorinated bottle, 25kg/drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃), well-ventilated warehouse away from incompatible substances. Keep away from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery.

78834-75-0 - Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

78834-75-0 - FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory Audit? Factory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

Transportation? By Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom Synthesis? Can provide custom synthesis services to best fit your research needs.

Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.

78834-75-0 - Safety Information:

HS Code

2918300090

78834-75-0 - Application:

Ethyl 7-Chloro-2-Oxoheptanoate (CAS: 78834-75-0) has been used in the preparation of pharmaceuticals such as Cilastatin (CAS: 82009-34-5) and Cilastatin Sodium (CAS: 81129-83-1). Cilastatin has antibacterial effects on Gram-positive and negative aerobic and anaerobes. The antibacterial spectrum includes Streptococcus, Staphylococcus aureus, Escherichia coli, Klebsiella, some strains of Acinetobacter, Haemophilus bacillus, Proteus, Serratia, Pseudomonas aeruginosa, etc. Clinically, Cilastatin is mainly used for respiratory tract infections, biliary tract infections, urinary system and abdominal cavity infections, skin and soft tissues, bones and joints, gynecological infections caused by gram-positive bacteria, negative bacteria, and anaerobic bacteria.
Cilastatin was designed to inhibit renal metabolism of Imipenem and prolong its half-life. Formulations containing Cilastatin in combination with Imipenem have been used to treat susceptible bacterial infections.