Fmoc-D-Leu-OH CAS 114360-54-2 N-Fmoc-D-Leucine Purity >99.0% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of N-Fmoc-D-Leucine (Fmoc-D-Leu-OH) (CAS: 114360-54-2) with high quality. Ruifu Chemical supplys a series of amino acids. We can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase Fmoc-D-Leu-OH, Please contact: alvin@ruifuchem.com
| Chemical Name | N-Fmoc-D-Leucine |
| Synonyms | Fmoc-D-Leu-OH; Fmoc-D-Leucine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-Leucine; N-9-Fluorenylmethoxycarbonyl-D-Leucine; (R)-Fmoc-2-Amino-4-Methylpentanoic Acid |
| Stock Status | In Stock, Production Capacity to Tons per Month |
| CAS Number | 114360-54-2 |
| Molecular Formula | C21H23NO4 |
| Molecular Weight | 353.42 g/mol |
| Melting Point | 153.0 to 160.0℃ |
| Density | 1.207±0.06 g/cm3 |
| Water Solubility | Insoluble in Water |
| Storage Temp. | Cool & Dry Place (2~8℃) |
| COA & MSDS | Available |
| Category | Fmoc-Amino Acids |
| Brand | Ruifu Chemical |
| Safety Statements | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. | ||
| WGK Germany | 3 | HS Code | 2922491990 |
| F | 10 | ||
| Items | Inspection Standards | Results |
| Appearance | White Powder | White Powder |
| Specific Rotation [α]20/D | +25.0°±2.0° (C=1 in DMF) |
+25.9° |
| Melting Point | 153.0 to 160.0℃ | 154.2℃ |
| TLC | ≥98.0% | >98.0% |
| Element Analysis (C、H、N) | ≤5.0% | <5.0% |
| Optical Purity | <0.50% L-Enantiomer | Complies |
| Clarity of Solution | 0.3 gram in 2ml DMF Clear Solution | Complies |
| Kaiser Test | <0.05% | <0.05% |
| Water by Karl Fischer | <1.00% | 0.103% |
| Loss on Drying | <1.00% (80℃, 2h) | 0.28% |
| Purity / Analysis Method | >99.0% (HPLC) | 99.64% |
| Mass Spectrum | In Accordance With the Standard | Complies |
| NMR Spectrum | In Accordance With the Standard | Complies |
| Conclusion | The product has been tested & complies with the specifications | |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
N-Fmoc-D-Leucine (Fmoc-D-Leu-OH) (CAS: 114360-54-2) is the N-Fmoc protected form of D-Leucine. D-Leucine, an unnatural isomer of L-Leucine. Fmoc-amino acids, used in peptide synthesis, used as an organic synthesis intermediate, pharmaceutical intermediate, biochemical reagent or chemical reagent.
A convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-Tryptophan methyl ester and N-Fmoc-D-Leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.
Synthesis method In the presence of alkali, 9-Fluorenomethoxycarbonyl chloride reacts with leucine to obtain Fmoc-D-Leucine. This method is simple to operate, The method of preparing Fmoc-D-Leucine with mild reaction conditions, high yield and wide applicability.
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