Fmoc-Gln(Trt)-OH CAS 132327-80-1 Purity >99.0% (HPLC) Factory

Short Description:

Nα-Fmoc-Nδ-Trityl-L-Glutamine

Synonyms: Fmoc-Gln(Trt)-OH 

CAS: 132327-80-1

Purity: >99.0% (HPLC)

Appearance: White Powder

Fmoc-Amino Acids, High Quality

Contact: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


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Description:

Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Nα-Fmoc-Nδ-Trityl-L-Glutamine (Fmoc-Gln(Trt)-OH) (CAS: 132327-80-1) with high quality. Ruifu Chemical supplys a series of amino acids. We can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase Fmoc-Gln(Trt)-OH, Please contact: alvin@ruifuchem.com

Chemical Properties:

Chemical Name Nα-Fmoc-Nδ-Trityl-L-Glutamine  
Synonyms Fmoc-Gln(Trt)-OH; Fmoc-L-Gln(Trt)-OH; Nalpha-Fmoc-Ndelta-Trityl-L-Glutamine; Nalpha-9-Fluorenylmethoxycarbonyl-Ndelta-Trityl-L-Glutamine
Stock Status In Stock 
CAS Number 132327-80-1
Molecular Formula C39H34N2O5
Molecular Weight 610.7 g/mol
Melting Point 150.0~170.0℃ 
Density 1.256±0.06 g/cm3 
Sensitive Moisture Sensitive
Storage Temp.  Cool & Dry Place (2~8℃) 
COA & MSDS Available
Category   Fmoc-Amino Acids 
Brand Ruifu Chemical

Specifications:

Items Inspection Standards Results
Appearance White Powder  White Powder
Purity / Analysis Method >99.0% (HPLC)  99.57%
Specific Rotation [α]20/D -14.5°±2.0° (C=1 in DMF)
-14.1°
Melting Point 150.0~170.0℃ 158.9~159.3℃
TLC  ≥98.0% >98.0%
Element Analysis (C、H、N) ≤5.0% <5.0%
Optical Purity <0.80% D-Enantiomer Not Detectable
Clarity of Solution 0.3 gram in 2ml DMF Clear Solution Complies
Kaiser Test <0.05% <0.05%
Water by Karl Fischer  <0.50% 0.13%
Residue on Ignition <0.20% Complies
Fmoc-β-Ala-OH <0.50% (HPLC)  Complies
Fmoc-β-Ala-Gln(Trt) -OH  <0.10% (HPLC)  Complies
Fmoc-Gln(Trt)-Gln(Trt)-OH <0.10% (HPLC)  Complies
Fmoc-Gln-OH <0.10% (HPLC)  Complies
Assay Free Amino Acid <0.20% (GC)  Complies
Ethyl Acetate <0.50% (GC)  Complies
IR Spectrum In Accordance With the Standard Complies 
Mass Spectrum In Accordance With the Standard Complies 
NMR Spectrum In Accordance With the Standard Complies 
Conclusion The product has been tested & complies with the given specifications

Package & Storage:

1. Reaction Process:

 www.ruifuchemical.com

2. The Residual Solvents:

 Ethyl Acetate, Petroleum Ether 

Package & Storage:

Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.

Advantages:

Sufficient Capacity: Sufficient facilities and technicians

Professional Service: One stop purchasing service

OEM Package: Custom package and label available

Fast Delivery: If within stock, three days delivery guaranteed

Stable Supply: Maintain reasonable stock    

Technical Support: Technology solution available

Custom Synthesis Service: Ranged from grams to kilos

High Quality: Established a complete quality assurance system

FAQ:

How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com 

15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.

Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.

Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.

Quality AssuranceStrict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

SamplesMost products provide free samples for quality evaluation, shipping cost should be paid by customers.

Factory AuditFactory audit welcome. Please make an appointment in advance.

MOQ? No MOQ. Small order is acceptable.

Delivery Time? If within stock, three days delivery guaranteed.

TransportationBy Express (FedEx, DHL), by Air, by Sea.

Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.

Custom SynthesisCan provide custom synthesis services to best fit your research needs.

Payment TermsProforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc. 

132327-80-1 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes R36/37/38 - Irritating to eyes, respiratory system and skin.
R53 - May cause long-term adverse effects in the aquatic environment
R43 - May cause sensitization by skin contact
Safety Description S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
S37 - Wear suitable gloves.
S24 - Avoid contact with skin.
WGK Germany 3
FLUKA BRAND F CODES 10-21
HS Code 2922491990

Application:

Nα-Fmoc-Nδ-Trityl-L-Glutamine (Fmoc-Gln(Trt)-OH) (CAS: 132327-80-1), is an amino acid derivative used in chemical synthesis and peptide chemistry.
Reaction type: Fmoc solid-phase peptide synthesis. Fmoc-amino acids, used in peptide synthesis, used as an organic synthesis intermediate, pharmaceutical intermediate, biochemical reagent or chemical reagent.
Fmoc-Gln(Trt)-OH in peptide synthesis prevents the possibility of the amide side chain from undergoing dehydration side reactions during activation, especially with carbodiimide reagents. Fmoc-Gln(Trt)-OH also has better solubility properties than Fmoc-Gln-OH. Fmoc-Gln(Trt)-OH dissolves readily in all standard peptide synthesis reagents, while Fmoc-Gln-OH is much less soluble in Dimethylformamide (DMF).
Fmoc-Gln(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Gln. Coupling can be performed by standard procedures. The trityl-protecting group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp.  

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